HK Akerblom, M Knip - Diabetes/Metabolism Research and Reviews - interscience.wiley.com Various environmental triggers, eg certain viruses and dietary factors, are thought to initiate the
autoimmune process, leading to the destruction of pancreatic -cells and consequent Type 1
diabetes. A genetic predisposition is another prerequisite allowing the autoimmune ... Cited by 175 - Related articles - BL Direct - All 6 versions
- ►nih.gov AL Notkins, A Lernmark - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig Type 1 diabetes, also known as either juvenile diabetes (because of the early age of onset) or
insulin-dependent diabetes mellitus (because of the clinical need for insulin), is now widely thought
to be an organ-specific autoimmune disease. Here we wish to summarize some generally ... Cited by 156 - Related articles - BL Direct - All 9 versions
- ►bmj.com SG Gardner, PJ Bingley, PA Sawtell, S Weeks, EAM … - British Medical Journal, 1997 - bmj.com The incidence of childhood diabetes has increased in Europe and many other parts of the world
over the past 20-30 years. 1 2 One of the best documented long term surveys has been in
Finland, which showed a 57% increase between 1965 and 1984 in children aged under ... Cited by 153 - Related articles - BL Direct - All 7 versions
H Hyöty, K Taylor - Diabetologia, 2002 - Springer Abstract. Viruses have long been considered a major environmental factor in the aetiology of
Type I (insu- lin-dependent) diabetes mellitus and recent work has greatly confirmed and extended
this role. In addition to the enteroviruses, there are several other viruses which, from time ... Cited by 146 - Related articles - BL Direct - All 3 versions
HK Akerblom, O Vaarala, H Hyoty, J … - American journal of …, 2002 - interscience.wiley.com * * Hans K. Åkerblom is an emeritus professor of pediatrics, University of Helsinki. He has over
the last two decades studied the epidemiology, etiology and pathogenesis, prediction and prevention
of type 1 diabetes in children. He is the Principal Investigator of the international ... Cited by 143 - Related articles - BL Direct - All 6 versions
M Lönnrot, K Korpela, M Knip, J Ilonen, O Simell, S … - Diabetes, 2000 - Am Diabetes Assoc Previous studies suggest that enterovirus infections may initiate and accelerate -cell damage
years before the clinical manifestation of type 1 diabetes. We have now analyzed the role of enterovirus
infections in the initiation of autoimmunity in children who have tested positive for ... Cited by 128 - Related articles - BL Direct - All 5 versions
- ►shouxi.net M Knip - Reviews in endocrine & metabolic disorders, 2003 - Springer Page 1. Reviews in Endocrine & Metabolic Disorders 2003;4:213–223 C 2003 Kluwer
Academic Publishers. Manufactured in The Netherlands. Environmental Triggers and
Determinants of Beta-Cell Autoimmunity and Type 1 Diabetes ... Cited by 108 - Related articles - BL Direct - All 12 versions
LL Field - Diabetologia, 2002 - Springer Family and twin studies have shown clearly that Type I (insulin-dependent) diabetes mellitus
has a ge- netic basis. However, only within the past decade has it been possible to systematically
attempt to identify the genes that increase susceptibility to this disorder using linkage and ... Cited by 110 - Related articles - BL Direct - All 4 versions
M Hiltunen, H Hyöty, M Knip, J Ilonen, H Reijonen, … - The Journal of infectious …, 1997 - jstor.org Islet Cell Antibody Seroconversion in Children Is Temporally Associated with ... Merja
Hiltunen, Heikki Hybty,* Mikael Knip, Jorma Ilonen, Helena Reijonen,* Paula Viihiisalo, Merja
Roivainen, Maria Loinnrot, Pauli Leinikki, Tapani Hovi, Hans K. Akerblom, and the ... Cited by 99 - Related articles - BL Direct - All 4 versions
