- ►nih.gov [PDF] R Duggirala, J Blangero, L Almasy, TD Dyer, … - The American Journal of Human Genetics, 1999 - Elsevier Since little is known about chromosomal locations harboring type 2
diabetes–susceptibility genes, we conducted a genomewide scan for such genes
in a Mexican American population. We used data from 27 low-income extended ... Cited by 213 - Related articles - BL Direct - All 5 versions
- ►endojournals.org S Matthaei, M Stumvoll, M Kellerer, HU Haring - Endocrine Reviews, 2000 - Endocrine Soc Diabetes mellitus type 2 is a world-wide growing health problem affecting more
than 150 million people at the beginning of the new millennium. It is believed
that this number will double in the next 25 yr. The pathophysiological ... Cited by 204 - Related articles - BL Direct - All 5 versions
JB Meigs, CIM Panhuysen, RH Myers, PWF … - Diabetes, 2002 - Am Diabetes Assoc Elevated blood glucose levels are the hallmark of type 2 diabetes as well as a
powerful risk factor for development of the disease. We conducted a genome-wide
search for diabetes-related genes, using measures of glycemia as ... Cited by 130 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] SA Schreyer, SC Chua Jr, RC LeBoeuf - Journal of Clinical Investigation, 1998 - pubmedcentral.nih.gov TNF- may play a role in mediating insulin resistance asso- ciated with obesity.
This concept is based on studies of obese rodents and humans, and cell culture
models. TNF elicits cellular responses via two receptors called p55 and ... Cited by 106 - Related articles - BL Direct - All 11 versions
I Barroso - Diabetic medicine, 2005 - interscience.wiley.com Type 2 diabetes (T2D) has become a health-care problem worldwide, with the rise
in disease prevalence being all the more worrying as it not only affects the
developed world but also developing nations with fewer resources to cope ... Cited by 101 - Related articles - All 6 versions
- ►171.66.122.45 PC Reifsnyder, G Churchill, EH Leiter - Genome Research, 2000 - 171.66.122.45 Obesity, a major risk factor for type II diabetes, is becoming more prevalent in
Western populations consuming high calorie diets while expending less energy
both at the workplace and at home. Most human obesity, and probably most ... Cited by 99 - Related articles - BL Direct - All 11 versions
A Jellema, MPA Zeegers, EJM Feskens, PC … - Diabetologia, 2003 - Springer Aims/hypothesis. Several case-control studies have ex- amined the association
between the Gly972Arg variant in the IRS-1 gene and Type 2 diabetes, but most
had limited power and results could therefore be conflict- ing. Methods. We ... Cited by 75 - Related articles - BL Direct - All 5 versions
R Culverhouse, T Klein, W Shannon - Genetic epidemiology, 2004 - interscience.wiley.com The restricted partition method (RPM) is a partitioning algorithm for examining
multi-locus genotypes as (potentially non-additive) predictors of a quantitative
trait. The motivating application was to develop a robust method to examine ... Cited by 70 - Related articles - BL Direct - All 4 versions
- ►nutrition.org SC Elbein - Journal of Nutrition, 1997 - Am Soc Nutrition Familial aggregation and concordance in monozygotic and dizygotic twins argue
strongly for a genetic etiology to noninsulin-dependent diabetes (NIDDM).
Nonetheless, studies of pathways implicated by the known physiology have ... Cited by 49 - Related articles - BL Direct - All 5 versions
