A Rabinovitch - Diabetes Metab Res Rev, 1998 - interscience.wiley.com Correlation studies between cytokines expressed in islets and autoimmune
diabetes development in NOD mice and BB rats have demonstrated that -cell
destructive insulitis is associated with increased expression of ... Cited by 342 - Related articles - BL Direct - All 3 versions
- ►nih.gov GR Hill, T Teshima, A Gerbitz, L Pan, KR … - Journal of Clinical Investigation, 1999 - Am Soc Clin Investig We demonstrate an increase in graft-versus-host disease (GVHD) after
experimental bone marrow transplant (BMT) when cyclophosphamide (Cy) is added to
an otherwise well-tolerated dose (900 cGy) of total body irradiation (TBI). ... Cited by 145 - Related articles - BL Direct - All 6 versions
- ►rupress.org ST Grey, MB Arvelo, W Hasenkamp, FH Bach, … - Journal of Experimental Medicine, 1999 - jem.rupress.org Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease resulting
from apoptotic destruction of ß cells in the islets of Langerhans. Low
expression of antioxidants and a predilection to produce nitric oxide (NO) ... Cited by 142 - Related articles - BL Direct - All 6 versions
- ►rupress.org SV Pakala, M Chivetta, CB Kelly, JD Katz - Journal of Experimental Medicine, 1999 - jem.rupress.org The islet-infiltrating and disease-causing leukocytes that are a hallmark of
insulin-dependent diabetes mellitus produce and respond to a set of cytokine
molecules. Of these, interleukin 1 , tumor necrosis factor (TNF)- , and ... Cited by 120 - Related articles - BL Direct - All 5 versions
T Mandrup-Poulsen - Diabetes, 2001 - Am Diabetes Assoc Pancreatic -cells are sensitive to a number of proapo- ptotic stimuli. Thus,
apoptosis is an important part of the physiological neonatal remodeling of the
endocrine pan- creas, and a number of pathological stimuli involved in type ... Cited by 117 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] M Arnush, MR Heitmeier, AL Scarim, MH … - Journal of Clinical Investigation, 1998 - pubmedcentral.nih.gov Resident macrophages have been suggested to participate in the initiation of
cell damage during the development of autoimmune diabetes. The purpose of this
study was to de- termine if the endogenous production and release of inter- ... Cited by 116 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org M Arnush, AL Scarim, MR Heitmeier, CB Kelly, … - The Journal of Immunology, 1998 - Am Assoc Immnol The purpose of this study was to evaluate the effects of resident islet
macrophage activation on ß cell function. Treatment of freshly isolated rat
islets with TNF- and LPS results in a potent inhibition of ... Cited by 83 - Related articles - BL Direct - All 3 versions
F de Strasbourg - Eur. J. Immunol, 1999 - journals.pasteur.ac.ir Insulin-dependent diabetes mellitus (IDDM) is not a disease of unbridled
destruction. The autoimmune attack on pancreatic beta cells has two distinct
stages – insulitis and diabetes – and progression of the former to the ... Cited by 74 - Related articles - View as HTML - BL Direct - All 4 versions
- ►jleukbio.org NR Barshes, S Wyllie, JA Goss - Journal of leukocyte biology, 2005 - Soc Leukocyte Biology Recent advances in clinical protocols have improved the outcomes of pancreatic
islet transplantation (PIT), yet PIT recipients typically require pancreatic
islet grafts derived from multiple donors to achieve insulin independence. ... Cited by 56 - Related articles - All 8 versions
HE Thomas, W Irawaty, R Darwiche, TC … - Diabetes, 2004 - Am Diabetes Assoc Proinflammatory cytokines are believed to be important in pancreatic β-cell
destruction in the development of type 1 diabetes. They act by upregulation of
genes including Fas and inducible nitric oxide synthase (iNOS), which have ... Cited by 51 - Related articles - BL Direct - All 4 versions
