- ►ucsf.edu [PDF] Y Falck-Ytter, ZM Younossi, G Marchesini, … - Seminars in Liver Disease, 2001 - thieme-connect.com Nonalcoholic steatohepatitis, along with other forms of nonalcoholic fatty liver
disease, is a chronic liver disease that is attracting increasing significance.
It is a clinicopathologic syndrome that was originally described in obese, ... Cited by 399 - Related articles - BL Direct - All 6 versions
DB Carr, KM Utzschneider, RL Hull, K Kodama … - Diabetes, 2004 - Am Diabetes Assoc The underlying pathophysiology of the metabolic syndrome is the subject of
debate, with both insulin resistance and obesity considered as important
factors. We evaluated the differential effects of insulin resistance and ... Cited by 346 - Related articles - BL Direct - All 5 versions
- ►endojournals.org Y Miyazaki, A Mahankali, M Matsuda, S … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc We examined the effect of pioglitazone on abdominal fat distribution to
elucidate the mechanisms via which pioglitazone improves insulin resistance in
patients with type 2 diabetes mellitus. Thirteen type 2 diabetic patients ... Cited by 334 - Related articles - BL Direct - All 8 versions
- ►endojournals.org H Bays, L Mandarino, RA DeFronzo - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance in liver
and muscle and impaired insulin secretion. Considerable evidence also implicates
deranged adipocyte metabolism and altered fat topography in the ... Cited by 245 - Related articles - All 4 versions
TJ Wilkin - Diabetologia, 2001 - Springer The definitions need urgent revision. More than half of the patients with Type I
diabetes present in adulthood, when their onset is slow and many do not develop
acidosis or require insulin for many years [1]. Type II diabetes occurs in ... Cited by 240 - Related articles - BL Direct - All 5 versions
JM Ye, PJ Doyle, MA Iglesias, DG Watson, … - Diabetes, 2001 - Am Diabetes Assoc Peroxisome proliferator—activated receptor (PPAR)-α agonists lower
circulating lipids, but the consequences for muscle lipid metabolism and insulin
sensitivity are not clear. We investigated whether PPAR-α activation ... Cited by 239 - Related articles - BL Direct - All 6 versions
R Roubenoff, VA Hughes - Journals of Gerontology Series A: Biological and …, 2000 - Geron Soc America Sarcopenia, the loss of muscle mass and strength with age, is becoming
recognized as a major cause of disability and morbidity in the elderly
population. Sarcopenia is part of normal aging and does not require a ... Cited by 230 - Related articles - BL Direct - All 2 versions
DE Moller, KD Kaufman, 2004 - Annual Reviews The metabolic syndrome is a cluster of interrelated common clinical disorders,
including obesity, insulin resistance, glucose intolerance, hypertension, and
dyslipidemia (hypertriglyceridemia and low HDL cholesterol levels). ... Cited by 228 - Related articles - All 6 versions
M Cnop, MJ Landchild, J Vidal, PJ Havel, NG … - Diabetes, 2002 - Am Diabetes Assoc Obesity is associated with insulin resistance, particularly when body fat has a
central distribution. However, insulin resistance also frequently occurs in
apparently lean individuals. It has been proposed that these lean insulin- ... Cited by 219 - Related articles - BL Direct - All 11 versions
I Gabriely, XH Ma, XM Yang, G Atzmon, MW … - Diabetes, 2002 - Am Diabetes Assoc Age-dependent changes in insulin action and body fat distribution are risk
factors for the development of type 2 diabetes. To examine whether the
accumulation of visceral fat (VF) could play a direct role in the ... Cited by 192 - Related articles - BL Direct - All 4 versions
