JN Marcus, CJ Aschkenasi, CE Lee, RM … - The Journal of comparative neurology, 2001 - interscience.wiley.com Orexins (hypocretins) are neuropeptides synthesized in the central nervous
system exclusively by neurons of the lateral hypothalamus. Orexin-containing
neurons have widespread projections and have been implicated in complex ... Cited by 364 - Related articles - BL Direct - All 4 versions
- ►cell.com CB Saper, TC Chou, JK Elmquist - Neuron, 2002 - Elsevier Feeding provides substrate for energy metabolism, which is vital to the survival
of every living animal and therefore is subject to intense regulation by brain
homeostatic and hedonic systems. Over the last decade, our understanding of ... Cited by 314 - Related articles - All 17 versions
TS Kilduff, C Peyron - Trends in Neurosciences, 2000 - Elsevier The molecules originally described as the hypocretins and subsequently as the
orexins were initially implicated in the control of food intake. Recent
observations implicate this newly-described neurotransmitter system in the ... Cited by 220 - Related articles - BL Direct - All 8 versions
- ►endocrinology-journals.org K Wynne, S Stanley, B McGowan, S Bloom - Journal of Endocrinology, 2005 - Soc Endocrinology Our understanding of the physiological systems that regulate food intake and
body weight has increased immensely over the past decade. Brain centres,
including the hypothalamus, brainstem and reward centres, signal via ... Cited by 170 - Related articles - All 4 versions
T Nakamura, K Uramura, T Nambu, T Yada, K … - Brain research, 2000 - Elsevier We demonstrated involvement of the ventral tegmental area (VTA) dopaminergic
system in orexin-induced hyperlocomotion and stereotypy in rats. In double-label
immunohistochemical study of rat brain, we found that tyrosine hydroxylase ... Cited by 140 - Related articles - All 3 versions
G Williams, JA Harrold, DJ Cutler - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Proceedings of the Nutrition Society (2000), 59, 385–396 ... Abbreviations:
AGRP, agouti gene-related peptide; ARC, arcuate nucleus; CNS, central nervous
system; DMH, dorsomedial hypothalamic nucleus; LHA, lateral hypothalamic ... Cited by 106 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org XJ Cai, ML Evans, CA Lister, RA Leslie, JRS … - Diabetes, 2001 - Am Diabetes Assoc Orexins are novel appetite-stimulating peptides expressed in the lateral
hypothalamic area (LHA), and their expression is stimulated by hypoglycemia in
fasted rats. We investigated activation of orexin and other neurons during ... Cited by 104 - Related articles - BL Direct - All 4 versions
- ►rockefeller.edu [PDF] SF Leibowitz, KE Wortley - Peptides, 2004 - Elsevier Energy balance is maintained via a homeostatic system involving both the brain
and the periphery. A key component of this system is the hypothalamus. Over the
past two decades, major advances have been made in identifying an ... Cited by 104 - Related articles - All 7 versions
- ►jneurosci.org TC Chou, CE Lee, J Lu, JK Elmquist, J Hara, … - Journal of Neuroscience, 2001 - Soc Neuroscience Orexins (also called hypocretins) are peptide neurotransmitters expressed in
neurons of the lateral hypothalamic area (LHA). Mice lacking the orexin peptides
develop narcolepsy-like symptoms, whereas mice with a selective loss of the ... Cited by 99 - Related articles - All 10 versions
- ►voeljemens.nl [PDF] A Peters, U Schweiger, L Pellerin, C Hubold, … - Neuroscience and biobehavioral reviews, 2004 - Elsevier The brain occupies a special hierarchical position in the organism. It is
separated from the general circulation by the blood-brain barrier, has high
energy consumption and a low energy storage capacity, uses only specific ... Cited by 97 - Related articles - All 8 versions
