- ►hematologylibrary.org S Vigouroux, E Yvon, E Biagi, MK Brenner - Blood, 2004 - bloodjournal.hematologylibrary.org Regulatory T cells participate in immunologic homeostasis by active suppression of inappropriate
immune responses. Regulatory T lymphocytes expressing CD4 and CD25 antigens and naturally
present in the peripheral blood were the first to be phenotypically characterized. ... Cited by 82 - Related articles - BL Direct - All 6 versions
EJ Ryan, LM Daly, KHG Mills - TRENDS in Biotechnology, 2001 - Elsevier Current paediatric immunization programmes include too many injections in the first months
of life. Oral or nasal vaccine delivery eliminates the requirement for needles and can induce
immunity at the site of infection. However, protein antigens are poorly immunogenic when ... Cited by 73 - Related articles - All 8 versions
- ►jimmunol.org EJ Ryan, E McNeela, M Pizza, R Rappuoli, L … - The Journal of …, 2000 - Am Assoc Immnol We have examined the roles of enzyme activity and the nontoxic AB complex of heat-labile toxin
(LT) from Escherichia coli on its adjuvant and immunomodulatory properties. LTK63, an LT mutant
that is completely devoid of enzyme activity, enhanced Th1 responses to coinjected Ags ... Cited by 61 - Related articles - BL Direct - All 3 versions
- ►five-plus.com.cn [PDF] J Zhang, X Wu, C Qin, J Qi, S Ma, H Zhang, Q Kong, … - Neurobiology of disease, 2003 - Elsevier Memory impairment progressing to dementia is the main clinical symptom of Alzheimer's disease
(AD). Deposition of the amyloid-β peptide (Aβ) in brain, particularly its 42-amino acid isoform
(Aβ42), has been shown to play a primary and crucial role in the pathogenesis of AD. In ... Cited by 56 - Related articles - All 6 versions
- ►diabetesjournals.org W Karges, K Pechhold, S Al Dahouk, I Riegger, M Rief, … - Diabetes, 2002 - Am Diabetes Assoc Insulin has been used to modify T-cell autoimmunity in experimental models of type 1
diabetes. In a large clinical trial, the effect of insulin to prevent type 1 diabetes is currently
investigated. We here show that insulin can adversely trigger autoimmune diabetes in two ... Cited by 37 - Related articles - BL Direct - All 5 versions
JE Carter III, WHR Langridge - Critical Reviews in Plant Sciences, 2002 - ingentaconnect.com Referee: Dr. Yoedono Sovyanhadi, Department of Biological Sciences, Oakwood College, 7000
Adventist Boulevard, NW, Huntsville, AL 35896 Over the last 2 decades, the number of emergent
infectious diseases has increased at an alarming rate. Also disheartening is the rise of ... Cited by 26 - Related articles - BL Direct - All 4 versions
KS Goudy, R Tisch - International reviews of immunology, 2005 - informahealthcare.com A major effort has been on-going to develop immunotherapies to prevent and/or treat type 1 diabetes
(T1D). This autoimmune disease is characterized by the selective loss of the insulin-producing
β cells via the cumulative effects of autoantigen-specific CD4 + and CD8 + T cells, ... Cited by 25 - Related articles - BL Direct - All 5 versions
S Bregenholt, M Wang, T Wolfe, A Hughes … - Scandinavian …, 2003 - interscience.wiley.com When conjugated to various proteins, the nontoxic B-chain of cholera toxin (CTB) significantly
increases the ability of these proteins to induce immunological tolerance after oral
administration. Here, we investigated if a nonconjugated form of CTB enhances the ... Cited by 26 - Related articles - BL Direct - All 5 versions
… , V Apostolopolous, D Homann, T Wolfe, A … - Clinical and …, 2003 - pubmedcentral.nih.gov Our earlier investigations have demonstrated a critical difference in the efficacy of orally administered
porcine compared to human or mouse insulin (no effect) in preventing type I diabetes in two distinct
experimental models. Based on these findings one has to assume that certain insulins ... Cited by 22 - Related articles - BL Direct - All 5 versions
A Hänninen, A Braakhuis, WR Heath, LC Harrison - Diabetes, 2001 - Am Diabetes Assoc Administration of antigens via mucosal routes, such as orally or intranasally, can induce specific
immunological tolerance and has been used as a rational basis for the treatment of autoimmune
diseases, including type 1 diabetes. Recently, however, orally delivered antigens were ... Cited by 21 - Related articles - BL Direct - All 4 versions
