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Scholar Results 1 - 10 of about 81 citing Xiang: Multiple metabolic defects during late pregnancy in women at high risk for type 2 diabetes. (0.09 sec) 

Preservation of pancreatic β-cell function and prevention of type 2 diabetes by …

- diabetesjournals.org
TA Buchanan, AH Xiang, RK Peters, SL Kjos, … - Diabetes, 2002 - Am Diabetes Assoc
Type 2 diabetes frequently results from progressive failure of pancreatic
β-cell function in the presence of chronic insulin resistance. We tested
whether chronic amelioration of insulin resistance would preserve ...
Cited by 926 - Related articles - BL Direct - All 6 versions

Gestational diabetes mellitus


SL Kjos, TA Buchanan - New England Journal of Medicine, 1999 - content.nejm.org
Gestational diabetes mellitus is defined as glucose intolerance that is first
detected during pregnancy. 1 This simple definition belies the complexity of a
condition that spans a spectrum of glycemia, pathophysiology, and clinical ...
Cited by 260 - Related articles - BL Direct - All 5 versions

Metformin therapy throughout pregnancy reduces the development of gestational diabetes …


CJ Glueck, P Wang, S Kobayashi, H Phillips, … - Fertility and sterility, 2002 - Elsevier
Patient(s): The prospective study included 33 nondiabetic women with PCOS who
conceived while taking metformin and had live births; of these, 28 were taking
metformin through delivery. The retrospective study included 39 nondiabetic ...
Cited by 226 - Related articles - BL Direct - All 11 versions

Accurate assessment of β-cell function

- diabetesjournals.org
RN Bergman, M Ader, K Huecking, G Van … - Diabetes, 2002 - Am Diabetes Assoc
Only in the last decade did modeling studies predict, and knockout experiments
confirm, that type 2 diabetes is a "2-hit" disease in which insulin resistance
is necessarily accompanied by ß-cell defect(s) preventing the compensatory ...
Cited by 171 - Related articles - BL Direct - All 4 versions

What is gestational diabetes?

- diabetesjournals.org
TA Buchanan, A Xiang, SL Kjos, R Watanabe - Diabetes Care, 2007 - Am Diabetes Assoc
Gestational diabetes mellitus (GDM) is defined as glucose intolerance with onset
or first recognition during pregnancy. As such, GDM is the product of routine
glucose tolerance screening that is currently carried out in otherwise ...
Cited by 170 - Related articles - BL Direct - All 17 versions

Gestational diabetes and insulin resistance: role in short-and long-term implications for …

- nutrition.org
PM Catalano, JP Kirwan, S Haugel-de Mouzon … - Journal of Nutrition, 2003 - Am Soc Nutrition
Gestational diabetes and obesity are the common metabolic abnormalities
occurring during pregnancy. Decreased maternal pregravid insulin sensitivity
(insulin resistance) coupled with an inadequate insulin response are the ...
Cited by 136 - Related articles - BL Direct - All 8 versions

Pancreatic B-cell defects in gestational diabetes: implications for the pathogenesis and …

- endojournals.org
TA Buchanan - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia that results
from tissue resistance to the glucose-lowering effects of insulin and inadequate
pancreatic B-cell compensation for that resistance (1). Longitudinal ...
Cited by 118 - Related articles - BL Direct - All 4 versions

Metformin during pregnancy reduces insulin, insulin resistance, insulin secretion, weight, …

- oxfordjournals.org
CJ Glueck, N Goldenberg, P Wang, M … - Human Reproduction, 2004 - ESHRE
BACKGROUND: In a prospective observational study of 42 pregnancies in 39
Caucasian women (age 30 ± 4 years) with polycystic ovary syndrome (PCOS), we
examined effects of metformin on maternal insulin, insulin resistance (IR), ...
Cited by 100 - Related articles - BL Direct - All 9 versions

Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus

- endojournals.org
C Homko, E Sivan, X Chen, EA Reece, G … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc
We have determined prehepatic insulin secretion rates (ISRs) in seven patients
with gestational diabetes mellitus (GDM) and in eight age- and weight-matched
nondiabetic pregnant women during late gestation (third trimester) and ...
Cited by 81 - Related articles - BL Direct - All 5 versions

Gestational diabetes: risk or myth?

- endojournals.org
TA Buchanan, SL Kjos - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc
There is a wide spectrum of views regarding the clinical significance of the
entity known as gestational diabetes mellitus (GDM). At one end of the spectrum
are advocates of strict evidence-based medical care who argue that there is ...
Cited by 68 - Related articles - BL Direct - All 4 versions


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