- ►diabetesjournals.org TA Buchanan, AH Xiang, RK Peters, SL Kjos, … - Diabetes, 2002 - Am Diabetes Assoc Type 2 diabetes frequently results from progressive failure of pancreatic
β-cell function in the presence of chronic insulin resistance. We tested
whether chronic amelioration of insulin resistance would preserve ... Cited by 926 - Related articles - BL Direct - All 6 versions
SL Kjos, TA Buchanan - New England Journal of Medicine, 1999 - content.nejm.org Gestational diabetes mellitus is defined as glucose intolerance that is first
detected during pregnancy. 1 This simple definition belies the complexity of a
condition that spans a spectrum of glycemia, pathophysiology, and clinical ... Cited by 260 - Related articles - BL Direct - All 5 versions
CJ Glueck, P Wang, S Kobayashi, H Phillips, … - Fertility and sterility, 2002 - Elsevier Patient(s): The prospective study included 33 nondiabetic women with PCOS who
conceived while taking metformin and had live births; of these, 28 were taking
metformin through delivery. The retrospective study included 39 nondiabetic ... Cited by 226 - Related articles - BL Direct - All 11 versions
- ►diabetesjournals.org RN Bergman, M Ader, K Huecking, G Van … - Diabetes, 2002 - Am Diabetes Assoc Only in the last decade did modeling studies predict, and knockout experiments
confirm, that type 2 diabetes is a "2-hit" disease in which insulin resistance
is necessarily accompanied by ß-cell defect(s) preventing the compensatory ... Cited by 171 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org TA Buchanan, A Xiang, SL Kjos, R Watanabe - Diabetes Care, 2007 - Am Diabetes Assoc Gestational diabetes mellitus (GDM) is defined as glucose intolerance with onset
or first recognition during pregnancy. As such, GDM is the product of routine
glucose tolerance screening that is currently carried out in otherwise ... Cited by 170 - Related articles - BL Direct - All 17 versions
- ►nutrition.org PM Catalano, JP Kirwan, S Haugel-de Mouzon … - Journal of Nutrition, 2003 - Am Soc Nutrition Gestational diabetes and obesity are the common metabolic abnormalities
occurring during pregnancy. Decreased maternal pregravid insulin sensitivity
(insulin resistance) coupled with an inadequate insulin response are the ... Cited by 136 - Related articles - BL Direct - All 8 versions
- ►endojournals.org TA Buchanan - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia that results
from tissue resistance to the glucose-lowering effects of insulin and inadequate
pancreatic B-cell compensation for that resistance (1). Longitudinal ... Cited by 118 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org CJ Glueck, N Goldenberg, P Wang, M … - Human Reproduction, 2004 - ESHRE BACKGROUND: In a prospective observational study of 42 pregnancies in 39
Caucasian women (age 30 ± 4 years) with polycystic ovary syndrome (PCOS), we
examined effects of metformin on maternal insulin, insulin resistance (IR), ... Cited by 100 - Related articles - BL Direct - All 9 versions
- ►endojournals.org C Homko, E Sivan, X Chen, EA Reece, G … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc We have determined prehepatic insulin secretion rates (ISRs) in seven patients
with gestational diabetes mellitus (GDM) and in eight age- and weight-matched
nondiabetic pregnant women during late gestation (third trimester) and ... Cited by 81 - Related articles - BL Direct - All 5 versions
- ►endojournals.org TA Buchanan, SL Kjos - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc There is a wide spectrum of views regarding the clinical significance of the
entity known as gestational diabetes mellitus (GDM). At one end of the spectrum
are advocates of strict evidence-based medical care who argue that there is ... Cited by 68 - Related articles - BL Direct - All 4 versions