S Soderberg, B Ahren, JH Jansson, O … - Journal of internal …, 1999 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 212 - Related articles - BL Direct - All 4 versions
- ►leptipro.org [PDF] G Sweeney - Cellular signalling, 2002 - Elsevier The identification of leptin as the product of the obesity (ob) gene has been followed by extensive
research identifying a wide spectrum of physiological effects elicited by this adipose-derived
hormone. These effects are mediated via a family of cytokine-like receptor isoforms ... Cited by 177 - Related articles - All 10 versions
- ►diabetesjournals.org C Vecchione, A Maffei, S Colella, A Aretini, R Poulet, G … - Diabetes, 2002 - Am Diabetes Assoc Recent evidence suggests that besides its action on the central nervous system, leptin can modulate
vascular tone through local mechanisms involving nitric oxide (NO) release. In this study, using
a fluorescent probe for direct determination of NO, we demonstrated both in endothelial ... Cited by 163 - Related articles - BL Direct - All 5 versions
AL Mark, MLG Correia, K Rahmouni, WG … - Journal of …, 2002 - journals.lww.com Leptin, an adipocyte secreted hormone, acts in the hypothalamus to inhibit appetite and promote
thermogenic metabolism, thereby reducing adiposity and body weight. Leptin has multiple autonomic
and cardiovascular actions, including sympathetic activation, increases in endothelium ... Cited by 133 - Related articles - BL Direct - All 6 versions
TJ Guzik, D Mangalat, R Korbut - Journal Of Physiology and Pharmacology, 2006 - jpp.krakow.pl Obesity and obesity related diseases are a major public health problem. Recent studies have
shown that fat tissue is not a simple energy storage organ, but exerts important endocrine and
immune functions. These are achieved predominantly through release of adipocytokines, ... Cited by 130 - Related articles - Cached - BL Direct - All 6 versions
- ►endocrinology-journals.org [PDF] J Ren - Journal of Endocrinology, 2004 - Soc Endocrinology The obese gene product, leptin, plays a central role in food intake and energy metabolism. The
physiological roles of leptin in human bodily function have been broadened over the past decade
since leptin was first discovered in 1994. Evidence has suggested that leptin plays a ... Cited by 128 - Related articles - BL Direct - All 10 versions
- ►ahajournals.org M Carlyle, OB Jones, JJ Kuo, JE Hall - Hypertension, 2002 - Am Heart Assoc Abstract— This study was designed to determine the role of changes in adrenergic activity in
mediating the chronic cardiovascular, renal, and metabolic actions of leptin. Male Sprague-Dawley
rats were implanted with catheters for mean arterial pressure (MAP) and heart rate (HR) ... Cited by 125 - Related articles - BL Direct - All 4 versions
P Kougias, H Chai, PH Lin, Q Yao, AB Lumsden, C … - Journal of Surgical …, 2005 - Elsevier Adipose tissue has recently emerged as an active endocrine organ that secretes a variety of
metabolically important substances, collectively called adipocytokines or adipokines. In this review
we summarize the effects of the adipokines leptin, adiponectin, and resistin on the ... Cited by 113 - Related articles - All 15 versions
S Engeli, AM Sharma - Journal of Molecular Medicine, 2001 - Springer Excessive accumulation of adipose tissue is associated with profound alterations in the cardiovascular
system, including increases in blood volume, heart rate, cardiac output, cardiac mass, and systemic
blood pressure [1, 2]. Obese individuals are also at a high risk for the develop- ment of ... Cited by 104 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org MW Nickola, LE Wold, PB Colligan, GJ Wang, WK … - Hypertension, 2000 - Am Heart Assoc Abstract—Obesity is commonly associated with impaired myocardial contractile function.
However, a direct link between these 2 states has not yet been established. There has been
an indication that leptin, the product of the human obesity gene, may play a role in obesity- ... Cited by 103 - Related articles - BL Direct - All 5 versions
