TH Luo, Y Zhao, G Li, WT Yuan, JJ Zhao, JL … - Diabetologia, 2001 - Springer Type II (non-insulin-dependent) diabetes mellitus is a major health problem in
many developed countries. In developing countries, like China, the prevalence of
Type II diabetes has statistically significantly in- creased in recent ... Cited by 115 - Related articles - BL Direct - All 3 versions
M Ristow - Journal of molecular medicine, 2004 - Springer Neurodegenerative disorders affect a major proportion of the general population,
especially with increasing age. Neurodegeneration is defined as progressive
impairment of any neuronal function. It either affects specific neu- rons ... Cited by 92 - Related articles - BL Direct - All 7 versions
- ►bmj.com MB Delatycki, R Williamson, SM Forrest - British Medical Journal, 2000 - jmg.bmj.com The eponymous description of the disease was proposed by Brousse in 1882. 6 Many
early publications are confused by the presence of cases, which are now
recognised not to have been FRDA. In particular, many cases that were ... Cited by 89 - Related articles - BL Direct - All 6 versions
- ►nih.gov M Ristow, H Mulder, D Pomplun, TJ Schulz, K … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of
insulin-producing β cells. We have disrupted expression of the mitochondrial
protein frataxin selectively in pancreatic β cells. Mice were born healthy ... Cited by 62 - Related articles - BL Direct - All 8 versions
L Hansen, O Pedersen - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com Throughout the last decade, molecular genetic studies of non-autoimmune diabetes
mellitus have contributed significantly to our present understanding of this
disease's complex aetiopathogenesis. Monogenic forms of diabetes ... Cited by 54 - Related articles - All 4 versions
AL Gloyn, MI McCarthy - Best Practice & Research Clinical Endocrinology & …, 2001 - Elsevier Type 2 diabetes mellitus is not a single disease but a genetically heterogenous
group of metabolic disorders sharing glucose intolerance. The precise underlying
biochemical defects are unknown and almost certainly include impairments of ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] J Hebinck, C Hardt, L Schöls, M Vorgerd, L … - Diabetes, 2000 - Am Diabetes Assoc Friedreich's ataxia (FA) is an autosomal recessive dis- ease that has been
attributed to a GAA triplet repeat expansion in the first intron of the
X25/frataxin gene. Impaired glucose tolerance is present in up to 39% of FA ... Cited by 12 - Related articles - BL Direct - All 6 versions
MI Shadrina, OV Miloserdova, PA Slominskii, … - Molecular Biology, 2002 - Springer Diabetes mellitus type 2 (DM-2) is a heteroge- neous disorder that is
characterized by disturbed car- bohydrate metabolism, hyperglycemia, and
glucosuria, and results from elevated insulin resistance of tissues and ... Cited by 6 - Related articles - BL Direct - All 7 versions
J Holmkvist, P Almgren, H Parikh, M Zucchelli … - European Journal of Human Genetics, 2005 - nature.com A GAA-repeat in the X25 gene is causing Friedreich's ataxia (FRDA), a common
neurodegenerative disease and >20% of FRDA patients develop type II diabetes
(T2D). Linkage has previously been detected between T2D and chromosome ... Cited by 3 - Related articles - All 5 versions
MF Bauer, S Hofmann, KD Gerbitz - Advances in Cell Aging and Gerontology, 2001 - csa.com Mitochondrial dysfunction in diabetes mellitus. Matthias F Bauer, Sabine
Hofmann, Klaus-Dieter Gerbitz Advances in Cell Aging and ... Cited by 1 - Related articles - All 2 versions
