- ►nih.gov R Duggirala, J Blangero, L Almasy, R Arya, TD … - The American Journal of Human Genetics, 2001 - Elsevier Insulin resistance and hyperinsulinemia are strong correlates of obesity and
type 2 diabetes, but little is known about their genetic determinants. Using
data on nondiabetics from Mexican American families and a multipoint ... Cited by 120 - Related articles - BL Direct - All 8 versions
- ►nih.gov CM Lindgren, MM Mahtani, E Widen, MI … - The American Journal of Human Genetics, 2002 - Elsevier Type 2 diabetes mellitus is a heterogeneous inherited disorder characterized by
chronic hyperglycemia resulting from pancreatic β-cell dysfunction and insulin
resistance. Although the pathogenic mechanisms are not fully understood, ... Cited by 116 - Related articles - BL Direct - All 9 versions
PO Kwiterovich… - The American journal of cardiology, 2002 - Elsevier Traditional risk factors for coronary artery disease (CAD) predict about 50% of
the risk of developing CAD. The Adult Treatment Panel (ATP) III has defined
emerging risk factors for CAD, including small, dense low-density ... Cited by 109 - Related articles - All 11 versions
- ►ahajournals.org LSC Cheng, RC Davis, LJ Raffel, AH Xiang, … - Circulation, 2001 - Am Heart Assoc From the Division of Medical Genetics (LS-CC, LJR, SP, JIR), Steven Spielberg
Pediatric Research Center, Cedars-Sinai Medical Center; the Departments of
Pediatrics (LS-CC, LJR, SP, JIR), Medicine (RCD, NW, MQ, P.-ZW, WAH, JIR), ... Cited by 74 - Related articles - BL Direct - All 5 versions
- Free from Publisher ZT Bloomgarden - Diabetes Care, 2003 - cat.inist.fr American Association of Clinical Endocrinologists(AACE) Consensus Conference on
the Insulin Resistance Syndrome: 25-26 August 2002, Washington, DC. ... Cited by 68 - Related articles - BL Direct - All 6 versions
EA McIntyre, M Walker - Clinical endocrinology, 2002 - interscience.wiley.com Both type 2 diabetes mellitus (T2DM) and insulin resistance are complex traits
in which multiple gene effects and metabolic and environmental factors combine
to contribute to the overall pathogenesis of these conditions. This ... Cited by 47 - Related articles - BL Direct - All 5 versions
CIM Panhuysen, LA Cupples, PWF Wilson, AG … - Diabetologia, 2003 - Springer Aims/hypothesis. Hyperinsulinaemia and insulin resis- tance usually precede
clinical hyperglycaemia and Type 2 diabetes. Thus, plasma insulin concentrations
and insulin resistance are important quantitative traits associated with ... Cited by 43 - Related articles - BL Direct - All 3 versions
- ►jhu.edu [PDF] G Cai, SA Cole, JH Freeland-Graves, JW … - Human Biology, 2004 - muse.jhu.edu Department of Genetics, Southwest Foundation for Biomedical Research, 7620 NW
Loop 410, San Antonio, TX 78227-5301. Department of Human Ecology, Nutrition
Division, University of Texas at Austin, Austin, TX. Cited by 26 - Related articles - All 7 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ... Cited by 28 - Related articles - BL Direct - All 4 versions