JW Goding, B Grobben, H Slegers - BBA-Molecular Basis of Disease, 2003 - Elsevier The ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP) multigene family
contains five members. NPP1-3 are type II transmembrane metalloenzymes
characterized by a similar modular structure composed of a short ... Cited by 100 - Related articles - All 4 versions
TJ Orchard, YF Chang, RE Ferrell, N Petro, DE … - Kidney international, 2002 - nature.com Kidney International aims to inform the renal researcher and practicing nephrologists
on all aspects of renal research. Clinical and basic renal research, commentaries ... Cited by 93 - Related articles - BL Direct - All 6 versions
BV Costanzo, V Trischitta, R Di Paola, D … - Diabetes, 2001 - Am Diabetes Assoc When overexpressed, the membrane glycoprotein PC-1 may play a role in human
insulin resistance through the inhibition of insulin receptor (IR)
autophosphorylation. A PC-1 variant (K 121 Q, with lysine 121 replaced by ... Cited by 76 - Related articles - BL Direct - All 5 versions
LH Canani, DPK Ng, A Smiles, JJ Rogus, JH … - Diabetes, 2002 - Am Diabetes Assoc A polymorphism in the ecto-nucleotide pyrophosphatase/phosphodiesterase 1 gene
(ENPP1) (previously known as PC-1), resulting in an amino acid change from
lysine to glutamine at codon 121 (K121Q), is associated with insulin ... Cited by 42 - Related articles - BL Direct - All 4 versions
N Matsuoka, A Patki, HK Tiwari, DB Allison, … - International Journal of Obesity, 2005 - nature.com To test for association of the ectonucleotide pyrophosphatase/phosphodiesterase
1 (ENPP1) K121Q polymorphism with body mass index (BMI) and diabetes in a large
sample of Caucasians and African-Americans by selectively genotyping ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►shouxi.net KG Ewens, RA George, K Sharma, FN … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic
variation contributes to risk of diabetic nephropathy. To assess the evidence
for specific susceptibility genes, we used the transmission/disequilibrium ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org L Tarnow, N Grarup, T Hansen, HH Parving, … - Nephrology Dialysis Transplantation, 2001 - ERA-EDTA Background. An XbaI polymorphism in the gene encoding the glucose transporter,
GLUT-1, is associated with development of diabetic nephropathy in Chinese type 2
diabetic patients. In addition, an amino acid variant (K121Q) in the gene ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] R Gijsbers, H Ceulemans, M Bollen - Biochemical Journal, 2003 - pubmedcentral.nih.gov The ubiquitous nucleotide pyrophosphatases\phosphodi- esterases NPP1–3 consist
of a short intracellular N-terminal domain, a single transmembrane domain and a
large extracellular part, comprising two somatomedin-B-like domains, a ... Cited by 22 - Related articles - BL Direct - All 11 versions
- Free from Publisher ML Stone, ME Craig, AK Chan, JW Lee, CF … - Diabetes Care, 2006 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— This study contained a longitudinal cohort of 972
patients; analysis of baseline risk factors was performed using logistic
regression and predictors over time using survival analysis. Albumin ... Cited by 22 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org SD Cosmo, G Miscio, L Zucaro, M Margaglione, A … - Nephrology Dialysis Transplantation, 2002 - ERA-EDTA Background. The DD genotype of the ACE gene predisposes to faster diabetic
nephropathy (DN) progression but its role in DN development is more
controversial. We reported previously, in type 1 diabetic patients, an ... Cited by 20 - Related articles - BL Direct - All 4 versions
