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Scholar Results 1 - 10 of about 183 citing Schuit: Glucose sensing in pancreatic β-cells. (0.12 sec) 

Critical role of cAMP-GEFII· Rim2 complex in incretin-potentiated insulin secretion


Y Kashima, T Miki, T Shibasaki, N Ozaki, M … - Journal of Biological Chemistry, 2001 - ASBMB
Incretins such as glucagon-like peptide-1 and gastric inhibitory
polypeptide/glucose-dependent insulinotropic peptide are known to potentiate
insulin secretion mainly through a cAMP/protein kinase A (PKA) signaling ...
Cited by 192 - Related articles - BL Direct - All 3 versions

Glucose-Dependent Insulinotropic Polypeptide Is a Growth Factor for {beta}(INS-1) Cells by …

- endojournals.org
A Trumper, K Trumper, H Trusheim, R Arnold, … - Molecular Endocrinology, 2001 - Endocrine Soc
Activation of the G-protein-coupled receptor for glucose-dependent
insulinotropic polypeptide facilitates insulin-release from pancreatic ß-cells.
In the present study, we examined whether glucose-dependent insulinotropic ...
Cited by 156 - Related articles - BL Direct - All 3 versions

Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis.


GA Rutter, GDS Xavier, I Leclerc - Biochemical Journal, 2003 - pubmedcentral.nih.gov
AMPK (5 -AMP-activated protein kinase) is emerging as a meta- bolic master
switch, by which cells in both mammals and lower organisms sense and decode
changes in energy status. Changes in AMPK activity have been shown to ...
Cited by 141 - Related articles - BL Direct - All 8 versions

[PDF] Neuropeptides, food intake and body weight regulation: a hypothalamic focus


JJG Hillebrand, D De Wied, RAH Adan - Peptides-New York, 2002 - saegre.org.ar
Energy homeostasis is controlled by a complex neuroendocrine system consisting
of peripheral signals like leptin and central signals, in particular,
neuropeptides. Several neuropeptides with anorexigenic (POMC, CART, and ...
Cited by 115 - Related articles - View as HTML - All 4 versions

Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus …


L Kang, VH Routh, EV Kuzhikandathil, LD … - Diabetes, 2004 - Am Diabetes Assoc
To evaluate potential mechanisms for neuronal glucosensing, fura-2 Ca 2+ imaging
and single-cell RT-PCR were carried out in dissociated ventromedial hypothalamic
nucleus (VMN) neurons. Glucose-excited (GE) neurons increased and glucose- ...
Cited by 94 - Related articles - BL Direct - All 7 versions

A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from …

- diabetesjournals.org
FM Gribble, L Williams, AK Simpson, F … - Diabetes, 2003 - Am Diabetes Assoc
Glucagon-like peptide 1 (GLP-1) secretion from intestinal l-cells is triggered
by luminal nutrients. We reported previously that glucose-triggered GLP-1
release from the l-cell model GLUTag involves closure of ATP-sensitive K + ...
Cited by 89 - Related articles - BL Direct - All 4 versions

Orexins in the brain-gut axis

- endojournals.org
AL Kirchgessner - Endocrine reviews, 2002 - Endocrine Soc
Orexins (hypocretins) are a novel pair of neuropeptides implicated in the
regulation of energy balances and arousal. Previous reports have indicated that
orexins are produced only in the lateral hypothalamic area, although orexin- ...
Cited by 89 - Related articles - BL Direct - All 4 versions

Molecular physiology of neuronal K-ATP channels (Review)

- kappa.ro [PDF] 
B Liss, J Roeper - Molecular Membrane Biology, 2001 - Informa Pharma Science
Summary ATP sensitive potassium (K-ATP) channels are widely expressed in many
cell types including neurons. K-ATP channels are heteromeric membrane proteins
thatconsist of two very different subunits: the pore-forming, ...
Cited by 77 - Related articles - BL Direct - All 11 versions

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase …


KJ Brocklehurst, VA Payne, RA Davies, D … - Diabetes, 2004 - Am Diabetes Assoc
Glucokinase (GK) has a major role in the control of blood glucose homeostasis
and is a strong potential target for the pharmacological treatment of type 2
diabetes. We report here the mechanism of action of two novel and potent ...
Cited by 76 - Related articles - BL Direct - All 6 versions

Glucose-sensing in glucagon-like peptide-1-secreting cells


F Reimann, FM Gribble - Diabetes, 2002 - Am Diabetes Assoc
Glucagon-like peptide-1 (GLP-1) is released from intestinal L-cells in response
to carbohydrate and fat in the diet. Despite the interest in GLP-1 as an
antidiabetic agent, very little is known about the mechanism of stimulus- ...
Cited by 72 - Related articles - BL Direct - All 5 versions


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