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Scholar Results 1 - 10 of about 31 citing Kato: Mechanism of amelioration of insulin resistance by β3-adrenoceptor agonist AJ-9677.... (0.10 sec) 

Metabolic and cellular plasticity in white adipose tissue I: effects of {beta} 3-adrenergic …

- physiology.org
JG Granneman, P Li, Z Zhu, Y Lu - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
Selective agonists of 3 -adrenergic receptors (Adrb3) exhibit potent
anti-diabetes properties in rodent models when given chronically, yet the
mechanisms involved are poorly understood. A salient feature of chronic ...
Cited by 39 - Related articles - BL Direct - All 4 versions

White adipose tissue contributes to UCP1-independent thermogenesis

- physiology.org
JG Granneman, M Burnazi, Z Zhu, LA … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
3 -Adrenergic receptors (AR) are nearly exclusively expressed in brown and white
adipose tissues, and chronic activation of these receptors by selective agonists
has profound anti-diabetes and anti-obesity effects. This study examined ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Uncoupling proteins--a new family of proteins with unknown function.


C Erlanson-Albertsson - Nutritional neuroscience, 2002 - ncbi.nlm.nih.gov
Uncoupling proteins are inner mitochondrial membrane proteins, which dissipate
the proton gradient, releasing the stored energy as heat. Five proteins have
been cloned, named UCP1, UCP2, UCP3, UCP4 and UCP5/BMCP1. These proteins ...
Cited by 27 - Related articles - BL Direct - All 2 versions

[PDF] Animal model in type 2 diabetes research: An overview


K Srinivasan, P Ramarao - Indian Journal of Medical Research, 2007 - icmr.nic.in
Type 2 diabetes is a complex and heterogeneous disorder presently affecting more
than 100 million people worldwide and causing serious socio-economic problems.
Appropriate experimental models are essential tools for understanding the ...
Cited by 25 - Related articles - View as HTML - BL Direct - All 3 versions

Metabolic and cellular plasticity in white adipose tissue II: role of peroxisome proliferator- …

- physiology.org
P Li, Z Zhu, Y Lu, JG Granneman - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
Chronic activation of adipocyte -adrenergic receptors induces remodeling of
white adipose tissue (WAT) that includes a transient inflammatory response
followed by mitochondrial biogenesis, induction of fatty acid oxidation ...
Cited by 24 - Related articles - BL Direct - All 5 versions

Mice Heterozygous for Tumor Necrosis Factor-α Converting Enzyme Are Protected From …

- shouxi.net
M Serino, R Menghini, L Fiorentino, R Amoruso … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE—Tumor necrosis factor (TNF)-α is known to affect insulin
sensitivity, glucose, and lipid metabolism through alternative and redundant
mechanisms at both translational and post-translational levels. TNF-α ...
Cited by 19 - Related articles - BL Direct - All 4 versions

Pharmacological approaches for the treatment of obesity


JA Fernandez-Lopez, X Remesar, M Foz, M … - Drugs, 2002 - ingentaconnect.com
Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . 915 1. Introduction . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 916 ...
Cited by 13 - Related articles - BL Direct - All 4 versions

New pharmacologic agents for diabetes


CJ Bailey - Current Diabetes Reports, 2001 - Springer
Future Treatment Strategies Future treatment strategies for type 2 diabetes are
expected to integrate existing and new agents against insulin resistance,
β-cell failure, and dyslipidemia to improve the prospect of attaining and ...
Cited by 9 - Related articles - BL Direct - All 2 versions

Recent Developments in the Design of Orally Bioavailable 3-Adrenergic Receptor Agonists


M Sawa, H Harada - Current medicinal chemistry, 2006 - ingentaconnect.com
Abstract: The β 3 -adrenergic receptor (β 3 -AR) has been shown to mediate
various pharmacological and physiological effects such as lipolysis,
thermogenesis, and relaxation of the urinary bladder. Activation of the β ...
Cited by 9 - Related articles - BL Direct - All 4 versions

beta3-Adrenergic Receptors: Really Relevant Targets for Anti-Obesity Drugs?


E Nisoli, C Tonello, MO Carruba - Current Medicinal Chemistry-Central Nervous System …, 2003 - ingentaconnect.com
Abstract: In simple terms, obesity is a chronic disorder of energy imbalance,
for which a long-term excess of energy intake over expenditure leads to the
storage of that excess energy as white adipose tissue. In this article, we ...
Cited by 9 - Related articles - BL Direct


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