AS Wagman, KW Johnson, DE Bussiere - Current pharmaceutical design, 2004 - ingentaconnect.com Abstract: Originally identified as a modulator of glycogen metabolism, glycogen
synthase kinase-3 (GSK3) is now understood to play an important regulatory role
in a variety of pathways including initiation of protein synthesis, cell ... Cited by 76 - Related articles - BL Direct - All 5 versions
M Ayaz, B Can, S Ozdemir, B Turan - Biological trace element research, 2002 - Springer One of the main causes leading to mortality in diabetes is myocardial disease.
Using streptozotocin (STZ)-induced diabetic animals, it has been possible to
characterize diabetes-induced myocardial abnormalities. Inter- stitial and ... Cited by 26 - Related articles - BL Direct - All 5 versions
MD Girón, JJ Caballero, AM Vargas, MD … - FEBS letters, 2003 - Elsevier Oral administration of sodium tungstate is an effective treatment for diabetes
in animal models. We examined the effects of 6 weeks of oral administration of
tungstate on glucose transporters (GLUT) in streptozotocin-induced diabetic ... Cited by 13 - Related articles - All 7 versions
CJ Bailey - Current Diabetes Reports, 2001 - Springer Future Treatment Strategies Future treatment strategies for type 2 diabetes are
expected to integrate existing and new agents against insulin resistance,
β-cell failure, and dyslipidemia to improve the prospect of attaining and ... Cited by 9 - Related articles - BL Direct - All 2 versions
A Gómez-Ramos, J Domínguez, D Zafra, H … - Journal of neuroscience research, 2006 - interscience.wiley.com Tungstate treatment increases the phosphorylation of glycogen synthase kinase-3
(GSK3 ) at serine 9, which triggers its inactivation both in cultured neural
cells and in vivo. GSK3 phosphorylation is dependent on the activation of ... Cited by 7 - Related articles - BL Direct - All 4 versions
JC Parker - Drugs of the Future, 2004 - journals.prous.com Glucose-6-phosphatase (G6Pase) is a multifunctional enzyme system that catalyzes
the final step in both the glycogenolytic and the gluconeogenic pathways,
cleaving phosphate from glucose-6-phosphate to liberate free glucose into ... Cited by 1 - Related articles - All 3 versions
JC Parker - Drugs of the Future, 2001 - journals.prous.com Currently, type 2 diabetes is treated with a combination of diet and exercise,
and then, if glycemic control is not achieved, with oral hypoglycemic agents
followed by (or supplemented with) insulin, if necessary. Insulin remains ... Related articles - All 2 versions
L Dharmarajan, CL Case, P Dunten, B … - FEBS journal, 2008 - interscience.wiley.com Tyr235 of GTP-dependent phosphoenolpyruvate (PEP) carboxykinase is a fully
invariant residue. The aromatic ring of this residue establishes an
energetically favorable weak anion–quadrupole interaction with PEP ... Related articles - All 5 versions
A Topic, M Milenkovic, S Uskokovic-Markovic, … - Biological Trace Element Research - Springer Abstract Investigations of effective, orally active, and safe antidiabetic
metallopharma- ceuticals have been carried out during the last two decades. It
has been reported that tungsten compounds mimic the action of insulin in ... Related articles
J Altirriba, A Barbera, H Del Zotto, B Nadal, … - BMC genomics, 2009 - biomedcentral.com Jordi Altirriba (jaltirri@clinic.ub.es) Albert Barbera (abarbera@clinic.ub.es)
Hector Del Zotto (hdelzotto@yahoo.com.ar) Belen Nadal (bnadal@ub.edu) Sandra
Piquer (spiquer@clinic.ub.es) Alex Sanchez-Pla (asanchez@ub.edu) Juan J ... Related articles - View as HTML - All 5 versions
