- ►aspetjournals.org [PDF] GA Gutman, KG Chandy, S Grissmer, M Lazdunski, D … - Pharmacological reviews, 2005 - ASPET GEORGE A. GUTMAN, K. GEORGE CHANDY, STEPHAN GRISSMER, MICHEL
LAZDUNSKI, DAVID MCKINNON, LUIS A. PARDO, GAIL A. ROBERTSON, BERNARDO
RUDY, MICHAEL C. SANGUINETTI, WALTER STU¨ HMER, AND XIAOLIANG WANG ... Cited by 131 - Related articles - BL Direct - All 9 versions
- ►aspetjournals.org NG Abraham, A Kappas - Pharmacological reviews, 2008 - ASPET This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological
states. The HO system includes the heme catabolic pathway, comprising HO and ... Cited by 89 - Related articles - All 6 versions
L Wu, M Ashraf, M Facci, R Wang, PG … - Proceedings of the …, 2004 - National Acad Sciences Imbalance between production and scavenging of superoxide anion results in hypertension
by the inactivation of nitric oxide, and the increased oxidative stress from the resultant peroxynitrite
that is produced promotes inflammatory processes such as atherosclerosis. Induction of ... Cited by 81 - Related articles - BL Direct - All 11 versions
- ►ahajournals.org JF Ndisang, W Zhao, R Wang - Hypertension, 2002 - Am Heart Assoc Heme oxygenase (HO) and carbon monoxide (CO) participate in the homeostatic control of cardiovascular
functions, including the regulation of blood pressure (BP). Upregulation of the HO/CO system
has been shown to lower BP in young (8 weeks) but not in adult (20 weeks) ... Cited by 64 - Related articles - BL Direct - All 6 versions
- ►physiology.org NG Abraham, R Rezzani, L Rodella, A … - American Journal of …, 2004 - Am Physiological Soc Heme oxygenase (HO)-1 represents a key defense mechanism against oxidative injury. Hyperglycemia
produces oxidative stress and various perturbations of cell physiology. The effect of streptozotocin
(STZ)-induced diabetes on aortic HO activity, heme content, the number of circulating ... Cited by 59 - Related articles - All 4 versions
S Quan, PM Kaminski, L Yang, T Morita, M Inaba, S … - … and Biophysical Research …, 2004 - Elsevier Heme oxygenase-1 (HO-1) represents a key defense mechanism against oxidative injury. Hyperglycemia
has been linked to increased oxidative stress, leading to endothelial dysfunction, delayed cell
replication, and enhanced apoptosis. The effect of streptozotocin (STZ)-induced diabetes ... Cited by 48 - Related articles - All 4 versions
W Durante - Vascular Medicine, 2002 - vmj.sagepub.com Abstract: Heme oxygenase (HO) catalyzes the degradation of heme to CO, iron, and
biliverdin. Biliverdin is subsequently metabolized to bilirubin by the enzyme biliverdin
reductase. Although long considered irrelevant byproducts of heme catabolism, recent ... Cited by 41 - Related articles - BL Direct - All 4 versions
L Wu, BHJ Juurlink - Journal of hypertension, 2001 - journals.lww.com The glutathione (GSH) system plays an important role in reducing oxidative stress, the increase
of which has been linked to the pathogenesis of hypertension. The aims of this study were to
investigate: (1) whether the GSH system was impaired in aortic smooth muscle cells ... Cited by 41 - Related articles - BL Direct - All 4 versions
R Hisaki, H Fujita, F Saito, T Kushiro - American Journal of Hypertension, 2005 - Elsevier The DS rats (n = 5 per group) were treated with 0.3% NaCl diets (LS), 8% NaCl diets (HS), and
8% NaCl diets plus 10 mmol/L tempol in drinking water (HS+T) for 5 weeks. Systolic blood pressure
(SBP) was measured by the tail-cuff method. As markers of renal damage, we measured ... Cited by 20 - Related articles - All 5 versions
