L Groop, M Orho-Melander - Journal of internal medicine, 2001 - interscience.wiley.com The first unifying definition for the metabolic syndrome was proposed by WHO in 1998. In accordance
to this, patients with type 2 diabetes mellitus or impaired glucose tolerane have the syndrome
if they fulfil two of the criteria: hypertension, dyslipidaemia, obesity/abdominal obesity and ... Cited by 246 - Related articles - BL Direct - All 4 versions
S Schinner, WA Scherbaum, SR Bornstein, A … - Diabetic …, 2005 - interscience.wiley.com Currently, we observe an epidemic expansion of diabetes mellitus. In subjects with Type 2 diabetes
the resistance of fat, muscle and liver to insulin is the central pathophysiological event in the
development of this disease. Genetic and environmental factors play a major role in this ... Cited by 71 - Related articles - All 5 versions
H Parikh, L Groop - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer About 150 million people suffer from type 2 diabetes in the world today and it has been predicted
that this num- ber will be doubled within 15 years [1]. It is no longer a disease of the elderly, age
at onset has decreased with the epidemic increase in prevalence. There are large eth- nic ... Cited by 62 - Related articles - BL Direct - All 3 versions
J Fredriksson, D Anevski, P Almgren, M Sjögren, V … - PLoS ONE, 2007 - pubmedcentral.nih.gov Polymorphisms in GYS1 (XbaIC>T) and APOE (-219G>T, ε2/ε3/ε4) were genotyped in 4,654
subjects participating in the Botnia T2D-family study and followed for a median of eight
years. Mortality analyses were performed using Cox proportional-hazards regression. ... Cited by 6 - Related articles - All 5 versions
Q Fk… - The Metabolic Syndrome AT The Beginning of The …, 2005 - books.google.com Genetic Susceptibility to the Metabolic Syndrome• 137 PPAR-gamma (Ala12 Allele) Npmotn
et al (Japanese*. Manrini fit al. Nemntn et al (. lapanesfi American). Oh pt al. Niskanen pt al. Simon
pt al. AltKhnlnr et al (SI SI). 5 Hpgple et al W ro Hasstedt et al. o 1 pi pt al.^ c Evans et al., ... Related articles