J Frystyk - Growth hormone & IGF research, 2004 - Elsevier IGF-I is a multipotent growth factor with important actions on normal tissue
growth and regeneration. In addition, IGF-I has been suggested to have
beneficial effects on glucose homeostasis due to its glucose lowering and ... Cited by 107 - Related articles - All 5 versions
CH Lang, TC Vary, RA Frost - Endocrinology, 2003 - Endocrine Soc This study examined whether the acute elevation of IGF-binding protein-1
(IGFBP-1) decreases the plasma free IGF-I concentration and alters in vivo rates
of muscle protein synthesis and glucose uptake. The plasma concentration of ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►endojournals.org CS Watson, P Bialek, M Anzo, J Khosravi, … - Endocrinology, 2006 - Endocrine Soc IGF binding protein-1 (IGFBP-1) inhibits the mitogenic actions of the IGFs.
Circulating IGFBP-1 is elevated in newborns and experimental animals with fetal
growth restriction (FGR). To establish a causal relationship between high ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►endojournals.org JG Scharf, F Dombrowski, R Novosyadlyy, C … - Endocrinology, 2004 - Endocrine Soc Hepatic stellate cells (HSC) play a pivotal role in hepatic tissue repair and
fibrogenesis. IGF-I has been considered a mitogenic signal for activation and
proliferation of HSC in vitro. In the present study IGF-I and IGF-binding ... Cited by 24 - Related articles - BL Direct - All 5 versions
VA Ezzat, ER Duncan, SB Wheatcroft, MT … - Diabetes, obesity & metabolism, 2008 - pt.wkhealth.com Patients with insulin resistance and type 2 diabetes have an excessive risk of
cardiovascular disease (CVD); this increased risk is not fully explained by
traditional risk factors such as hypertension and dyslipidaemias. There is ... Cited by 19 - Related articles - BL Direct - All 5 versions
- ►jbc.org K Sakai, HB Lowman, DR Clemmons - Journal of Biological Chemistry, 2002 - ASBMB Insulin-like growth factor-binding protein (IGFBP)-1 binds to insulin-like
growth factor (IGF)-I and -II with high affinity and has been shown to modulate
IGF-I actions in vivo and in vitro. The synthesis of IGFBP-1 is suppressed ... Cited by 17 - Related articles - BL Direct - All 8 versions
- ►endocrinology-journals.org J Beattie, K Phillips, JH Shand, M … - Journal of molecular endocrinology, 2005 - Soc Endocrinology Insulin-like growth factor binding proteins (IGFBPs) -3 and -5 are known to
interact with various components of the extracellular matrix (ECM; eg heparin
and heparan sulphate) and this interaction is believed to affect the ... Cited by 14 - Related articles - All 4 versions
- ►ebmonline.org V Cingel-Ristic, BF Schrijvers, AK van Vliet, … - Experimental Biology and Medicine, 2005 - SEBM Insulin-like growth factor I (IGF-I) accumulates in the kidney following the
onset of diabetes, initiating diabetic renal hypertrophy. Increased renal IGF-I
protein content, which is not reflected in messenger RNA (mRNA) levels, ... Cited by 5 - Related articles - All 5 versions
