T Rankinen, L Pérusse, SJ Weisnagel, EE Snyder, YC … - Obesity, 2002 - nature.com This report constitutes the eighth update of the human obesity gene map, incorporating published
results up to the end of October 2001. Evidence from the rodent and human obesity cases caused
by single-gene mutations, Mendelian disorders exhibiting obesity as a clinical feature, ... Cited by 146 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org SL Kirstein, PA Insel - Pharmacological reviews, 2004 - ASPET Pharmacogenetics, the inherited basis for interindividual differences in drug response, has rapidly
expanded with the advent of new molecular tools and the sequencing of the human
genome, yielding pharmacogenomics. We review here recent ideas and findings ... Cited by 80 - Related articles - BL Direct - All 10 versions
A Loktionov - The Journal of Nutritional Biochemistry, 2003 - Elsevier Rapid progress in human genome decoding has accelerated search for the role of gene polymorphisms
in the pathogenesis of complex multifactorial diseases. This review summarizes the results of
recent studies on the associations of common gene variants with multifactorial chronic ... Cited by 71 - Related articles - All 8 versions
CM Damcott, P Sack, AR Shuldiner - … and metabolism clinics of North America, 2003 - Elsevier Obesity has become an epidemic in the United States and worldwide. The 1999–2000 National
Health and Nutrition Examination Survey (NHANES) estimated that 64% of the adult population
of the United States is either overweight or obese (body mass index [BMI] >25 kg/m 2 ), ... Cited by 48 - Related articles - BL Direct - All 3 versions
D Jaquet, DA Trégouët, T Godefroy, V Nicaud, D … - Diabetes, 2002 - Am Diabetes Assoc It has been suggested that the insulin resistance (IR) associated with reduced fetal growth results
from interactions between genetic factors and an unfavorable fetal environment. In addition, the
adipose tissue seems to play a key role in this association. We investigated whether ... Cited by 45 - Related articles - BL Direct - All 4 versions
A Halverstadt, DA Phares, RE Ferrell, KR Wilund, AP … - Metabolism, 2003 - Elsevier Plasma high-density lipoprotein cholesterol (HDL-C) levels are an important independent risk
factor for cardiovascular disease (CVD) that can be modified through exercise training.
However, levels of HDL-C and its subfractions and their response to standardized ... Cited by 43 - Related articles - All 10 versions
KM Small, SB Liggett - Trends in Pharmacological Sciences, 2001 - Elsevier For each α 2 -adrenoceptor subtype (α 2A , α 2B and α 2C ), sequence variationswithin the coding
region of each gene have been identified in humans. These result in substitutions or deletions
of amino acids in the third intracellular loops of each receptor. This article summarizes the ... Cited by 35 - Related articles - All 5 versions
P Heinonen, L Jartti, MJ Jarvisalo, U Pesonen, … - Clinical …, 2002 - cs.portlandpress.com A deletion variant of the a 2B -adrenergic receptor (a 2B -AR) has been associated with an increased
risk of acute cardiac events in middle-aged men. Our aim was to determine the possible associations
between the a 2B -AR gene deletion variant and indicators of subclinical atherosclerosis ... Cited by 29 - Related articles - Cached - BL Direct - All 13 versions
- ►endojournals.org N Suzuki, T Matsunaga, K Nagasumi, T … - Journal of Clinical …, 2003 - Endocrine Soc Several polymorphisms of genes involved in autonomic nervous system (ANS) function have
been reported to affect metabolic regulation. We have investigated the association of an 2B
-adrenergic receptor ( 2B AR) three-amino acid deletion polymorphism with ANS activity ... Cited by 26 - Related articles - BL Direct - All 4 versions
MM Mercado, JC McLenithan, KD Silver, AR … - Current Diabetes Reports, 2002 - Springer Insulin resistance, defined as the decreased ability of insulin to performits biological
functions, is likely to represent the primary physiologic defect underlying the insulin resistance
syndrome (IRS), which includes insulin resistance/hyper- insulinemia, glucose ... Cited by 20 - Related articles - BL Direct - All 2 versions
