- ►kosen21.org [PDF] MW Schwartz, D Porte Jr - Science, 2005 - sciencemag.org Recent evidence suggests a key role for the brain in the control of both body fat content and glucose
metabolism. Neuronal systems that regulate energy intake, energy expenditure, and endogenous
glucose production sense and respond to input from hormonal and nutrient-related ... Cited by 268 - Related articles - All 12 versions
R Gruetter - Journal of neuroscience research, 2003 - interscience.wiley.com The brain contains a significant amount of glycogen that is an order of magnitude smaller than
that in muscle, but several-fold higher than the cerebral glucose content. Although the precise
role of brain glycogen to date is unknown, it seems affected by focal activation, ... Cited by 74 - Related articles - BL Direct - All 7 versions
IY Choi, H Lei, R Gruetter - Journal of Cerebral Blood Flow & Metabolism, 2002 - nature.com The effect of deep barbiturate anesthesia on brain glucose transport, TCA cycle flux, and
aspartate, glutamate, and glutamine metabolism was assessed in the rat brain in vivo using 13
C nuclear magnetic resonance spectroscopy at 9.4 T in conjunction with [1- 13 C] glucose ... Cited by 64 - Related articles - BL Direct - All 3 versions
SC Woods, TA Lutz, N Geary, W … - … Transactions of the …, 2006 - rstb.royalsocietypublishing.org The control of food intake and body weight by the brain relies upon the detection and integration
of signals reflecting energy stores and fluxes, and their interaction with many different inputs
related to food palatability and gastrointestinal handling as well as social, emotional, ... Cited by 40 - Related articles - BL Direct - All 9 versions
A Convit - Neurobiology of aging, 2005 - Elsevier Cognitive function and peripheral glucose regulation both decrease with age. There is a consistent
and growing literature reporting memory and other cognitive problems among individuals with
diabetes mellitus as well as those with pre-diabetes. There are two papers in the literature ... Cited by 31 - Related articles - All 10 versions
AL McCall - European journal of pharmacology, 2004 - Elsevier The brain uses glucose as its primary fuel. Cerebral metabolism of glucose requires transport
through the blood–brain barrier, glycolytic conversion to pyruvate, metabolism via the tricarboxylic
acid cycle and ultimately oxidation to carbon dioxide and water for full provision of ... Cited by 31 - Related articles - All 5 versions
K Anthony, LJ Reed, JT Dunn, E Bingham, D Hopkins, … - Diabetes, 2006 - Am Diabetes Assoc The rising prevalence of obesity and type 2 diabetes is a global challenge. A possible mechanism
linking insulin resistance and weight gain would be attenuation of insulin-evoked responses
in brain areas relevant to eating in systemic insulin resistance. We measured brain ... Cited by 27 - Related articles - BL Direct - All 6 versions
AB Criego, I Tkac, A Kumar, W Thomas, R … - Journal of …, 2005 - interscience.wiley.com Although it is well established that recurrent hypoglycemia leads to hypoglycemia
unawareness, the mechanisms responsible for this are unknown. One hypothesis is that recurrent
hypoglycemia alters brain glucose transport or metabolism. We measured steady-state ... Cited by 26 - Related articles - All 3 versions
