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Scholar Results 1 - 10 of about 45 citing Reimann: Structural basis for the interference between nicorandil and sulfonylurea action. (0.12 sec) 

Sulphonylurea action revisited: the post-cloning era


FM Gribble, F Reimann - Diabetologia, 2003 - Springer
Hypoglycaemic agents such as sulphonylureas and the newer group of
“glinides” stimulate insulin secretion by closing ATP-sensitive potassium (K
ATP ) channels in pancreatic beta cells, but have varying cross-reac- ...
Cited by 107 - Related articles - BL Direct - All 3 versions

Impairment of myocardial protection in type 2 diabetic patients

- endojournals.org
TM Lee, TF Chou - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
EPIDEMIOLOGICAL STUDIES HAVE shown that diabetic patients are more prone to
develop postinfarction complications (1). Moreover, diabetic patients with
ischemic heart disease have a substantially worse outcome after coronary ...
Cited by 99 - Related articles - BL Direct - All 6 versions

Pharmacological agents that directly modulate insulin secretion

- aspetjournals.org
ME Doyle, JM Egan - Pharmacological reviews, 2003 - ASPET
Blood glucose levels are sensed and controlled by the release of hormones from
the islets of Langerhans in the pancreas. The -cell, the insulin-secreting cell
in the islet, can detect subtle increases in circulating glucose levels and ...
Cited by 80 - Related articles - BL Direct - All 8 versions

KATP channel openers: structure-activity relationships and therapeutic potential


R Mannhold - Medicinal Research Reviews, 2004 - interscience.wiley.com
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Cited by 66 - Related articles - BL Direct - All 5 versions

ATP-sensitive potassium channels


GC Rodrigo, NB Standen - Current pharmaceutical design, 2005 - ingentaconnect.com
INTRODUCTION Adenosine triphosphate-sensitive potassium channels (K ATP
channels) were discovered in the early 1980s in cardiac muscle and pancreatic
β-cells [1-4], and have since been identified in many other cells and ...
Cited by 48 - Related articles - All 4 versions

Pharmacological modulation of KATP channels


F Gribble, F Reimann - Biochemical Society Transactions, 2002 - bst.portlandpress.com
Pharmacological modulation of ATP-sensitive K + (K ATP ) channels is used in the
treatment of a number of clinical conditions, including type 2 diabetes and
angina. The sulphonylureas and related drugs, which are used to treat type ...
Cited by 43 - Related articles - Cached - BL Direct - All 10 versions

Sulfonylureas and cardiovascular effects: from experimental data to clinical use. Available …

- alfediam.org [PDF] 
JP Riveline, N Danchin, F Ledru, M Varroud- … - Diabetes and Metabolism, 2003 - Elsevier
The main molecule studied is glibenclamide (GB). In vitro and in animal studies,
GB is both deleterious for ischemic preconditionning (IPC) and protective for
arrhythmia during acute ischemia. Glimepiride (GM) and gliclazide (GCZ) do ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Gliclazide modified release

- adisonline.com [PDF] 
JK McGavin, CM Perry, KL Goa - Drugs, 2002 - ingentaconnect.com
Abstract h Gliclazide modified release (MR) is a new formulation of the drug
gliclazide and is given once daily. The hydrophilic matrix of hypromellose-based
polymer in the new formula- tion effects a progressive release of the drug ...
Cited by 30 - Related articles - BL Direct - All 6 versions

Differential selectivity of insulin secretagogues Mechanisms, clinical implications, and drug …


FM Gribble, F Reimann - Journal of diabetes and its complications, 2003 - Elsevier
The sulphonylurea receptor (SUR) subunits of K ATP channels are the targets for
several classes of therapeutic drugs. Sulphonylureas close K ATP channels in
pancreatic β-cells and are used to stimulate insulin release in type 2 ...
Cited by 25 - Related articles - All 7 versions

Role of previous treatment with sulfonylureas in diabetic patients with acute myocardial …


N Danchin, G Charpentier, F Ledru, L Vaur, P … - Diabetes/Metabolism Reviews - interscience.wiley.com
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Cited by 24 - Related articles - All 3 versions


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