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Scholar Results 1 - 10 of 12 citing Berkovich: Inducible and reversible β-cell autoimmunity and hyperplasia in transgenic mice.... (0.12 sec) 

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation


D Ahuja, MT Sáenz-Robles, JM Pipas - Oncogene, 2005 - nature.com
DNA tumor viruses such as simian virus 40 (SV40) express dominant acting
oncoproteins that exert their effects by associating with key cellular targets
and altering the signaling pathways they govern. Thus, tumor viruses have ...
Cited by 106 - Related articles - BL Direct - All 6 versions

Tools for targeted manipulation of the mouse genome

- physiology.org
L van der Weyden, DJ Adams, A Bradley - Physiological Genomics, 2002 - Am Physiological Soc
In the postgenomic era the mouse will be central to the challenge of ascribing a
function to the 40,000 or so genes that constitute our genome. In this review,
we summarize some of the classic and modern approaches that have fueled the ...
Cited by 98 - Related articles - BL Direct - All 3 versions

Differentiation of human liver-derived, insulin-producing cells toward the β-cell phenotype

- shouxi.net
M Zalzman, L Anker-Kitai, S Efrat - Diabetes, 2005 - Am Diabetes Assoc
Type 1 diabetes is caused by autoimmune destruction of the pancreatic islet
insulin-producing β-cells. Insulin administration does not prevent long-term
complications of the disease, as the optimal insulin dosage is difficult to ...
Cited by 70 - Related articles - BL Direct - All 5 versions

Expansion and redifferentiation of adult human pancreatic islet cells


L Ouziel-Yahalom, M Zalzman, L Anker-Kitai, S … - Biochemical and Biophysical Research …, 2006 - Elsevier
Type 1 diabetes is caused by autoimmune destruction of the pancreatic islet
insulin-producing β cells. Insulin administration does not prevent long-term
complications of the disease, since the optimal insulin dosage is difficult ...
Cited by 52 - Related articles - All 4 versions

[PDF] Controlled gene activation and inactivation in the mouse


M Mallo - Front Biosci, 2006 - bioscience.org
The emergence of techniques that allow fine manipulation of gene expression in
the mouse have changed the way biomedically relevant processes are studied, as
they allow their analysis in the living animal. In addition, this has ...
Cited by 14 - Related articles - View as HTML - All 3 versions

Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and …

- cjb.net
KHJ Park, JL Hallows, P Chakrabarty, P Davies … - Journal of Neuroscience, 2007 - neuro.cjb.net
A large body of evidence has shown the activation of a cohort of cell cycle
regulators and the duplication of DNA in degenerating neurons of Alzheimer's
disease (AD) brain. Activation of these regulators and duplication of ...
Cited by 13 - Related articles - All 3 versions

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro

- nih.gov
Y Bar, HA Russ, S Knoller, L Ouziel-Yahalom, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—In vitro expansion of β-cells from adult human islets could solve
the tissue shortage for cell replacement therapy of diabetes. Culture of human
islet cells typically results in <16 cell doublings and loss of insulin ...
Cited by 3 - Related articles - All 4 versions

Generation and characterization of islet cell tumor in pTet-on/pTRE-SV40Tag double- …


Q Shen, Q Sun, X Wei, J Dong, R Zhang, P Wu, … - Journal of bioscience and bioengineering, 2007 - Elsevier
A line of double-transgenic mice that develop neoplasms arising primarily in the
pancreas was established. In these mice, the oncogene SV40 T antigen (Tag) was
detected in the pancreas with and without the control of Tet-on system. The ...
Cited by 3 - Related articles - BL Direct - All 10 versions

Investigation of the age-at-onset heterogeneity in type 1 diabetes through mathematical …


X Wang, Z He, S Ghosh - Mathematical biosciences, 2006 - Elsevier
The heterogeneity between young- and adult-onset type 1 diabetes (T1D) is well
known, but not well understood. We approach this question through mathematical
formulation and analysis of the dynamic interactions between the immune ...
Cited by 2 - Related articles - All 4 versions

[PDF] HES-1 Is Involved in Adaptation of Adult Human ß-Cells to Proliferation In Vitro


Y Bar, HA Russ, S Knoller, L Ouziel-Yahalom, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—In vitro expansion of -cells from adult human islets could solve the
tissue shortage for cell replacement therapy of diabetes. Culture of human islet
cells typically results in 16 cell doublings and loss of insulin ...


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