- ►jlr.org JM Brown, MS Boysen, SS Jensen, RF Morrison, J … - The Journal of Lipid …, 2003 - ASBMB Trans-10,cis-12 conjugated linoleic acid (CLA) has previously been shown to be the CLA isomer
responsible for CLA-induced reductions in body fat in animal models, and we have shown that
this isomer, but not the cis-9,trans-11 CLA isomer, specifically decreased triglyceride (TG) ... Cited by 98 - Related articles - BL Direct - All 4 versions
D LeRoith - The American journal of medicine, 2002 - Elsevier Defects in insulin action and insulin secretion are both present in type 2 diabetes, and both are
believed to be genetically predetermined. In the absence of a defect in β-cell function, individuals
can compensate indefinitely for insulin resistance with appropriate hyperinsulinemia, as ... Cited by 89 - Related articles - All 7 versions
OS Gardner, BJ Dewar, HS Earp, JM Samet, LM … - Journal of Biological …, 2003 - ASBMB Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that function
as ligand-activated transcription factors regulating lipid metabolism and homeostasis. In addition
to their ability to regulate PPAR-mediated gene transcription, PPAR and ligands have ... Cited by 63 - Related articles - BL Direct - All 5 versions
S Perrini, A Natalicchio, L Laviola, G Belsanti, C … - Diabetes, 2004 - Am Diabetes Assoc Dehydroepiandrosterone (DHEA) has been shown to modulate glucose utilization in humans
and animals, but the mechanisms of DHEA action have not been clarified. We show that DHEA
induces a dose- and time-dependent increase in glucose transport rates in both 3T3-L1 ... Cited by 40 - Related articles - BL Direct - All 4 versions
D Lann, D LeRoith - Medical Clinics of North America, 2007 - Elsevier Classically, the metabolic syndrome is characterized as group of pathologies including visceral
obesity, hypertension, dyslipidemia, and impaired glucose tolerance. It is now realized that insulin
resistance plays a principal role in initiating and perpetuating the pathologic ... Cited by 26 - Related articles - All 25 versions
- ►physiology.org Z He, T Jiang, Z Wang, M Levi, J Li - American Journal of …, 2004 - Am Physiological Soc Carbohydrate response element-binding protein (ChREBP) is a rat homolog of human
Williams-Beuren syndrome region 14 and a member of the basic helix-loop-helix leucine zipper
transcription factor family. Its activation was found to be inducible by carbohydrate in the ... Cited by 21 - Related articles - All 3 versions
LH Young - The American journal of medicine, 2003 - Elsevier A high rate of myocardial metabolism is needed to generate energy to sustain cardiac contractile
activity. Typically, energy generation occurs through the metabolism of free fatty acids
(FFAs), glucose, and lactate. However, in individuals who are insulin resistant or who ... Cited by 13 - Related articles - All 4 versions
J Huang, SH Hsia, T Imamura, I Usui, JM Olefsky - Endocrinology, 2004 - Endocrine Soc The target genes of peroxisomal proliferator-activated receptor- ligands that lead to insulin sensitization
are not fully understood. In this study, we have found that the thiazolidinedione, troglitazone,
increases expression of annexin II at both the mRNA and protein levels, raising the ... Cited by 8 - Related articles - BL Direct - All 4 versions
M Hoenig, DC Ferguson - American journal of veterinary research, 2003 - Am Vet Med Assoc Materials and Methods Cats—Four lean and 18 obese female neutered adult pur- pose-bred
catsa (age range, 3.5 to 4.1 years) were used in this study. The cats had been neutered at approximately
8 months of age. The cats were allocated into 3 groups: group L consist- ed of the 4 lean ... Cited by 6 - Related articles - BL Direct - All 3 versions
