- ►jbc.org LGD Fryer, A Parbu-Patel, D Carling - Journal of Biological Chemistry, 2002 - ASBMB AMP-activated protein kinase (AMPK) is activated within the cell in response to
multiple stresses that increase the intracellular AMP:ATP ratio. Here we show
that incubation of muscle cells with the thiazolidinedione, rosiglitazone, ... Cited by 495 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org AJ Gilde, KAJM van der Lee, PHM Willemsen, G … - Circulation Research, 2003 - Am Heart Assoc Long-chain fatty acids (FA) coordinately induce the expression of a panel of
genes involved in cellular FA metabolism in cardiac muscle cells, thereby
promoting their own metabolism. These effects are likely to be mediated by ... Cited by 180 - Related articles - BL Direct - All 6 versions
- ►upenn.edu [PDF] HB Hartman, X Hu, KX Tyler, CK Dalal, MA … - Journal of Biological Chemistry, 2002 - ASBMB Resistin, also known as AdipocyteSecreted Factor (ADSF) and Found inInflammatory
Zone 3 (FIZZ3), is a mouse protein with potential roles in insulin resistance
and adipocyte differentiation. The resistin gene is expressed almost ... Cited by 154 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org R Cunard, M Ricote, D DiCampli, DC Archer, … - The Journal of Immunology, 2002 - Am Assoc Immnol Peroxisome proliferator activated receptors (PPARs) are ligand-activated
transcription factors with diverse actions including adipocyte differentiation
and lipid metabolism. Recent studies have revealed anti-inflammatory ... Cited by 142 - Related articles - BL Direct - All 4 versions
DL Feinstein, A Spagnolo, C Akar, G … - Biochemical Pharmacology, 2005 - Elsevier Agonists of the peroxisome proliferator activated receptor gamma (PPARĪ³) are
currently used for treatment of type 2 diabetes due to their insulin sensitizing
and glucose metabolism stabilizing effects. More recently some of these ... Cited by 127 - Related articles - All 4 versions
- ►shouxi.net I Bogacka, H Xie, GA Bray, SR Smith - Diabetes, 2005 - Am Diabetes Assoc Thiazolidenediones such as pioglitazone improve insulin sensitivity in diabetic
patients by several mechanisms, including increased uptake and metabolism of
free fatty acids in adipose tissue. The purpose of the present study was to ... Cited by 120 - Related articles - All 5 versions
- ►diabetesjournals.org B Brunmair, K Staniek, F Gras, N Scharf, A … - Diabetes, 2004 - Am Diabetes Assoc Metformin and thiazolidinediones (TZDs) are believed to exert their antidiabetic
effects via different mechanisms. As evidence suggests that both impair cell
respiration in vitro, this study compared their effects on mitochondrial ... Cited by 110 - Related articles - BL Direct - All 5 versions
K Kotarsky, NE Nilsson, E Flodgren, C Owman … - Biochemical and Biophysical Research …, 2003 - Elsevier Fatty acids, which are essential nutritional components, are also involved in
cardiovascular and metabolic diseases. Here we report a human cell surface
receptor that we name free fatty acid receptor (FFAR), because it is ... Cited by 109 - Related articles - BL Direct - All 4 versions
- ►endojournals.org Y Li, MA Lazar - Molecular Endocrinology, 2002 - Endocrine Soc The PPAR is a key adipogenic determination factor. Ligands for PPAR such as
antidiabetic thiazolidinedione (TZD) compounds are adipogenic, and many
adipocyte genes that are activated by TZDs contain binding sites for PPAR . ... Cited by 69 - Related articles - BL Direct - All 5 versions
