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Scholar Results 1 - 10 of about 76 citing Hevener: Thiazolidinedione treatment prevents free fatty acid–induced insulin resistance.... (0.11 sec) 

PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3


SH Koo, H Satoh, S Herzig, CH Lee, S Hedrick … - Nature medicine, 2004 - nature.com
Cited by 215 - Related articles - BL Direct - All 5 versions

Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance …

- nih.gov
AW Norris, L Chen, SJ Fisher, I Szanto, M … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
Activation of peroxisome proliferator-activated receptor γ (PPARγ) by
thiazolidinediones (TZDs) improves insulin resistance by increasing
insulin-stimulated glucose disposal in skeletal muscle. It remains ...
Cited by 209 - Related articles - BL Direct - All 6 versions

Adenovirus-mediated chronic “hyper-resistinemia” leads to in vivo insulin resistance in …

- nih.gov
H Satoh, MTA Nguyen, PDG Miles, T Imamura, … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
We investigated the chronic in vivo effect of resistin on insulin sensitivity
and glucose metabolism by overexpressing resistin protein in male Wistar rats
using intravenous administration of an adenovirus encoding mouse resistin. ...
Cited by 159 - Related articles - BL Direct - All 7 versions

Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes

- diabetesjournals.org
J Tonelli, W Li, P Kishore, UB Pajvani, E … - Diabetes, 2004 - Am Diabetes Assoc
Whereas thiazolidinediones (TZDs) are known to rapidly improve insulin action in
animals, short durations of TZD therapy have never been studied in humans. Among
the many known actions of TZDs, increased circulating levels of the high ...
Cited by 143 - Related articles - BL Direct - All 5 versions

Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin …

- nih.gov
L Wilson-Fritch, A Burkart, G Bell, K … - Molecular and Cellular Biology, 2003 - Am Soc Microbiol
White adipose tissue is an important endocrine organ involved in the control of
whole-body metabolism, insulin sensitivity, and food intake. To better
understand these functions, 3T3-L1 cell differentiation was studied by ...
Cited by 136 - Related articles - BL Direct - All 8 versions

Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to …

- diabetesjournals.org
GK Bandyopadhyay, JG Yu, J Ofrecio, JM … - Diabetes, 2006 - Am Diabetes Assoc
Increased accumulation of fatty acids and their derivatives can impair
insulin-stimulated glucose disposal by skeletal muscle. To characterize the
nature of the defects in lipid metabolism and to evaluate the effects of ...
Cited by 78 - Related articles - BL Direct - All 5 versions

Chronic leptin administration decreases fatty acid uptake and fatty acid transporters in rat …


GR Steinberg, DJ Dyck, J Calles-Escandon, … - Journal of Biological Chemistry, 2002 - ASBMB
Chronic leptin administration reduces triacylglycerol content in skeletal
muscle. We hypothesized that chronic leptin treatment, within physiologic
limits, would reduce the fatty acid uptake capacity of red and white ...
Cited by 74 - Related articles - BL Direct - All 6 versions

Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents …


JM Ye, N Dzamko, ME Cleasby, BD Hegarty, … - Diabetologia, 2004 - Springer
Aims/hypothesis. Thiazolidinediones can enhance clearance of whole-body
non-esterified fatty acids and protect against the insulin resistance that
develops during an acute lipid load. The present study used [ 3 H]-R- ...
Cited by 72 - Related articles - BL Direct - All 4 versions

Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 …


G Boden, P Cheung, M Mozzoli, SK Fried - Metabolism, 2003 - Elsevier
The current study aimed to compare the effects of treatment (2 months) with
thiazolidinediones (TZDs) and placebo on glucose and fat metabolism in patients
with type 2 diabetes (T2DM) in a crossover design. Eight patients received ...
Cited by 70 - Related articles - All 10 versions

Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F- …


JK Kim, JJ Fillmore, O Gavrilova, L Chao, T … - Diabetes, 2003 - Am Diabetes Assoc
To determine the role of adipocytes and the tissue-specific nature in the
insulin sensitizing action of rosiglitazone, we examined the effects of 3 weeks
of rosiglitazone treatment on insulin signaling and action during ...
Cited by 60 - Related articles - BL Direct - All 5 versions


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