- ►nih.gov AW Norris, L Chen, SJ Fisher, I Szanto, M … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig Activation of peroxisome proliferator-activated receptor γ (PPARγ) by
thiazolidinediones (TZDs) improves insulin resistance by increasing
insulin-stimulated glucose disposal in skeletal muscle. It remains ... Cited by 209 - Related articles - BL Direct - All 6 versions
- ►nih.gov H Satoh, MTA Nguyen, PDG Miles, T Imamura, … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig We investigated the chronic in vivo effect of resistin on insulin sensitivity
and glucose metabolism by overexpressing resistin protein in male Wistar rats
using intravenous administration of an adenovirus encoding mouse resistin. ... Cited by 159 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org J Tonelli, W Li, P Kishore, UB Pajvani, E … - Diabetes, 2004 - Am Diabetes Assoc Whereas thiazolidinediones (TZDs) are known to rapidly improve insulin action in
animals, short durations of TZD therapy have never been studied in humans. Among
the many known actions of TZDs, increased circulating levels of the high ... Cited by 143 - Related articles - BL Direct - All 5 versions
- ►nih.gov L Wilson-Fritch, A Burkart, G Bell, K … - Molecular and Cellular Biology, 2003 - Am Soc Microbiol White adipose tissue is an important endocrine organ involved in the control of
whole-body metabolism, insulin sensitivity, and food intake. To better
understand these functions, 3T3-L1 cell differentiation was studied by ... Cited by 136 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org GK Bandyopadhyay, JG Yu, J Ofrecio, JM … - Diabetes, 2006 - Am Diabetes Assoc Increased accumulation of fatty acids and their derivatives can impair
insulin-stimulated glucose disposal by skeletal muscle. To characterize the
nature of the defects in lipid metabolism and to evaluate the effects of ... Cited by 78 - Related articles - BL Direct - All 5 versions
GR Steinberg, DJ Dyck, J Calles-Escandon, … - Journal of Biological Chemistry, 2002 - ASBMB Chronic leptin administration reduces triacylglycerol content in skeletal
muscle. We hypothesized that chronic leptin treatment, within physiologic
limits, would reduce the fatty acid uptake capacity of red and white ... Cited by 74 - Related articles - BL Direct - All 6 versions
JM Ye, N Dzamko, ME Cleasby, BD Hegarty, … - Diabetologia, 2004 - Springer Aims/hypothesis. Thiazolidinediones can enhance clearance of whole-body
non-esterified fatty acids and protect against the insulin resistance that
develops during an acute lipid load. The present study used [ 3 H]-R- ... Cited by 72 - Related articles - BL Direct - All 4 versions
G Boden, P Cheung, M Mozzoli, SK Fried - Metabolism, 2003 - Elsevier The current study aimed to compare the effects of treatment (2 months) with
thiazolidinediones (TZDs) and placebo on glucose and fat metabolism in patients
with type 2 diabetes (T2DM) in a crossover design. Eight patients received ... Cited by 70 - Related articles - All 10 versions
JK Kim, JJ Fillmore, O Gavrilova, L Chao, T … - Diabetes, 2003 - Am Diabetes Assoc To determine the role of adipocytes and the tissue-specific nature in the
insulin sensitizing action of rosiglitazone, we examined the effects of 3 weeks
of rosiglitazone treatment on insulin signaling and action during ... Cited by 60 - Related articles - BL Direct - All 5 versions