TA Pearson, GA Mensah, RW Alexander, JL … - Circulation, 2003 - Am Heart Assoc In 1998, the American Heart Association convened Prevention Conference V to
examine strategies for the identification of high-risk patients who need primary
prevention. Among the strategies discussed was the measurement of markers ... Cited by 2065 - Related articles - BL Direct - All 9 versions
P Dandona, A Aljada, A Bandyopadhyay - TRENDS in Immunology, 2004 - Elsevier Recent data have revealed that the plasma concentration of inflammatory
mediators, such as tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6),
is increased in the insulin resistant states of obesity and type 2 ... Cited by 528 - Related articles - All 4 versions
- ►diabetesjournals.org DJ Freeman, J Norrie, MJ Caslake, A Gaw, I … - Diabetes, 2002 - Am Diabetes Assoc Accumulating evidence implicates inflammation as a potential pathway in the
pathogenesis of type 2 diabetes. The objective of the present study was to
assess the ability of C-reactive protein (CRP) to predict the development ... Cited by 467 - Related articles - BL Direct - All 7 versions
- ►endojournals.org JM Fernandez-Real, W Ricart - Endocrine Reviews, 2003 - Endocrine Soc Insulin resistance is increasingly recognized as a chronic, low-level,
inflammatory state. Hyperinsulinemia and insulin action were initially proposed
as the common preceding factors of hypertension, low high-density ... Cited by 430 - Related articles - BL Direct - All 5 versions
- ►nih.gov SE Shoelson, J Lee, AB Goldfine - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Over a hundred years ago, high doses of salicylates were shown to lower glucose
levels in diabetic patients. This should have been an important clue to link
inflammation to the pathogenesis of type 2 diabetes (T2D), but the ... Cited by 414 - Related articles - BL Direct - All 11 versions
- ►ahajournals.org RJ Aviles, DO Martin, C Apperson-Hansen, … - Circulation, 2003 - Am Heart Assoc From the Department of Cardiovascular Medicine (RJA, DOM, DRVW, MSL, MKC),
Department of Biostatistics (CA-H., PLH), The Cleveland Clinic Foundation,
Cleveland, Ohio; Cardiovascular Health Research Unit (BMP), University of ... Cited by 400 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org PM Ridker, PWF Wilson, SM Grundy - Circulation, 2004 - Am Heart Assoc Of novel risk factors for cardiovascular disease currently under investigation,
high-sensitivity C-reactive protein (hsCRP) is the most promising. To date, more
than 20 prospective epidemiologic studies have demonstrated that hsCRP ... Cited by 367 - Related articles - All 8 versions
- Free from Publisher JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase
response (sometimes called low-grade inflammation, but part of a widespread
activation of the innate immune system) is closely involved in the ... Cited by 362 - Related articles - BL Direct - All 8 versions
- ►physiology.org AMW Petersen, BK Pedersen - Journal of Applied Physiology, 2005 - Am Physiological Soc Regular exercise offers protection against all-cause mortality, primarily by
protection against cardiovascular disease and Type 2 diabetes mellitus. The
latter disorders have been associated with chronic low-grade systemic ... Cited by 322 - Related articles - All 10 versions
J Spranger, A Kroke, M Möhlig, K Hoffmann, … - Diabetes, 2003 - Am Diabetes Assoc A subclinical inflammatory reaction has been shown to precede the onset of type
2 (non-insulin-dependent) diabetes. We therefore examined prospectively the
effects of the central inflammatory cytokines interleukin (IL)-1β, IL-6, ... Cited by 317 - Related articles - BL Direct - All 5 versions