S Milewski - Biochimica et Biophysica Acta (BBA)/Protein …, 2002 - Elsevier -Glutamine: -fructose-6-phosphate amidotransferase, known under trivial name of
glucosamine-6-phosphate synthase, as the only member of the amidotransferase
subfamily of enzymes, does not display any ammonia-dependent activity. This ... Cited by 60 - Related articles - All 7 versions
KC Chou - Journal of Proteome Research, 2004 - gordonlifescience.org Many lines of evidences indicate that increased flux of glucose through the
pathway, in which glutamine: fructose-6-phosphate amidotransferase (GFPT or
GFAT) is a key catalyst while uridine-5′-diphosphate- N-acetylglucosamine ... Cited by 44 - Related articles - View as HTML - All 5 versions
- ►jbc.org KO Broschat, C Gorka, JD Page, CL Martin- … - Journal of Biological Chemistry, 2002 - ASBMB Glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first
committed step in the pathway for biosynthesis of hexosamines in mammals. A
member of the N-terminal nucleophile class of amidotransferases, GFAT ... Cited by 29 - Related articles - BL Direct - All 5 versions
C Weigert, K Klopfer, C Kausch, K Brodbeck, … - Diabetes, 2003 - Am Diabetes Assoc The nutrient sensing capacity of the hexosamine biosynthetic pathway (HBP) has
been implicated in the development of insulin resistance of skeletal muscle. To
study the molecular mechanism of the free fatty acid (FFA)-induced ... Cited by 27 - Related articles - BL Direct - All 4 versions
P Anderle, T Sengstag, DM Mutch, M Rumbo, V … - BMC genomics, 2005 - biomedcentral.com We have characterized the mRNA expression profiles of 76 % of all currently
known transporters along the anterior-posterior axis of the gut. This is the
first study to describe the expression profiles of the majority of all ... Cited by 18 - Related articles - Cached - All 8 versions
- ►mcponline.org J Zitzler, D Link, R Schafer, W Liebetrau, M … - Molecular & Cellular Proteomics, 2004 - ASBMB We describe a novel genetic screen that is performed by transfecting every
individual clone of an expression clone collection into a separate population of
cells in a high-throughput mode. We combined high-throughput functional ... Cited by 14 - Related articles - BL Direct - All 3 versions
DPK Ng, WH Walker, KS Chia, S Choo, JH … - Diabetes, 2004 - Am Diabetes Assoc Glutamine-fructose-6-phosphate transaminase 1 (GFAT) is the rate-limiting enzyme
of the hexosamine pathway that has been implicated in the pathogenesis of
diabetic nephropathy. As such, we hypothesized that GFPT1, which encodes ... Cited by 9 - Related articles - BL Direct - All 5 versions
LP Singh, M Alexander, K Greene, ED Crook - Journal of Investigative Medicine, 2003 - journals.lww.com Hyperglycemia-induced alterations in mesangial cell function and extracellular
matrix protein (ECM) accumulation are seen in diabetic glomerulopathy. The
hexosamine biosynthesis pathway (HBP) is implicated in mediating several ... Cited by 7 - Related articles - BL Direct - All 4 versions
P Durand, B Golinelli-Pimpaneau, S … - Archives of Biochemistry and Biophysics, 2008 - Elsevier The hexosamine biosynthetic pathway starts from d-fructose-6-phosphate (Fru6P) 2
which is produced from glucose via the glycolysis pathway. The Fru6P is
converted into d-glucosamine-6-phosphate (GlcN6P) by the rate-limiting ... Cited by 5 - Related articles - All 4 versions
- ►tokushima-u.ac.jp [PDF] K Kunika, T Tanahashi, E Kudo, N Mizusawa, … - Journal of Human Genetics, 2006 - Springer Abstract Glutamine: fructose-6-phosphate amido- transferase 1 (GFPT1) acts as a
rate-limiting enzyme in the hexosamine biosynthetic pathway, which is an
alternative branch of glucose metabolism. To evaluate GFPT1 as a ... Cited by 2 - Related articles - BL Direct - All 8 versions
