- ►nih.gov JD Horton, JL Goldstein, MS Brown - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig Lipid homeostasis in vertebrate cells is regulated by a family of membrane-bound
transcription factors designated sterol regulatory element–binding proteins
(SREBPs). SREBPs directly activate the expression of more than 30 genes ... Cited by 1122 - Related articles - BL Direct - All 15 versions
G Liang, J Yang, JD Horton, RE Hammer, JL … - Journal of Biological Chemistry, 2002 - ASBMB Two treatments, fasting/refeeding and administration of liver X receptor (LXR)
agonists, elevate the mRNA for sterol regulatory element-binding protein-1c
(SREBP-1c) and enhance lipid synthesis in liver. These treatments do not ... Cited by 261 - Related articles - BL Direct - All 5 versions
- ►nih.gov BA Laffitte, LC Chao, J Li, R Walczak, S … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences The control of lipid and glucose metabolism is closely linked. The nuclear
receptors liver X receptor (LXR)α and LXRβ have been implicated in gene
expression linked to lipid homeostasis; however, their role in glucose ... Cited by 226 - Related articles - BL Direct - All 10 versions
F Foufelle, P Ferré - BIOCHEMICAL JOURNAL-LONDON-, 2002 - bj.portlandpress.com The regulation of hepatic glucose metabolism has a key role in whole-body energy
metabolism, since the liver is able to store (glycogen synthesis, lipogenesis)
and to produce (glycogenolysis, gluconeogenesis) glucose. These pathways ... Cited by 220 - Related articles - View as HTML - BL Direct - All 9 versions
D Eberle, B Hegarty, P Bossard, P Ferre, F … - Biochimie, 2004 - Elsevier Sterol regulatory element binding proteins (SREBPs) are a family of
transcription factors that regulate lipid homeostasis by controlling the
expression of a range of enzymes required for endogenous cholesterol, fatty ... Cited by 185 - Related articles - All 3 versions
- ►physiology.org A Barthel, D Schmoll - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc The regulation of hepatic gluconeogenesis is an important process in the
adjustment of the blood glucose level, and pathological changes in the glucose
production of the liver are a central characteristic in type 2 diabetes. ... Cited by 123 - Related articles - BL Direct - All 3 versions
- ►nih.gov S Shimba, N Ishii, Y Ohta, T Ohno, Y Watabe … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences Brain and muscle Arnt-like protein-1 (BMAL1; also known as MOP3 or Arnt3) is a
transcription factor known to regulate circadian rhythm. Here, we established
its involvement in the control of adipogenesis and lipid metabolism ... Cited by 111 - Related articles - BL Direct - All 10 versions
NB Ruderman, H Park, VK Kaushik, D Dean, S … - Acta Physiologica Scandinavica, 2003 - interscience.wiley.com An increasing body of evidence has revealed that activation of adenosine
monophosphate (AMP)-activated protein kinase (AMPK)-activated protein kinase
increases fatty acid oxidation by lowering the concentration of malonyl ... Cited by 76 - Related articles - BL Direct - All 4 versions
- ►psu.edu [PDF] H Lan, ME Rabaglia, JP Stoehr, ST Nadler, KL … - Diabetes, 2003 - Am Diabetes Assoc Obesity is a strong risk factor for the development of type 2 diabetes. We have
previously reported that in adipose tissue of obese (ob/ob) mice, the expression
of adipogenic genes is decreased. When made genetically obese, the BTBR ... Cited by 77 - Related articles - BL Direct - All 15 versions
- ►umin.ne.jp [PDF] H Ono, H Shimano, H Katagiri, N Yahagi, H … - Diabetes, 2003 - Am Diabetes Assoc Akt is critical in insulin-induced metabolism of glucose and lipids. To
investigate functions induced by hepatic Akt activation, a constitutively active
Akt, NH 2 -terminally myristoylation signal-attached Akt (myr-Akt), was ... Cited by 68 - Related articles - BL Direct - All 6 versions
