- ►angrylapdog.com AJ van der Lely, M Tschop, ML Heiman, E … - Endocrine Reviews, 2004 - edrv.endojournals.org.p.angrylapdog.com Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays
strong GH-releasing activity. This activity is mediated by the activation of the
so-called GH secretagogue receptor type 1a. This receptor had been shown to ... Cited by 425 - Related articles - BL Direct - All 9 versions
- ►physiology.org M Kojima, K Kangawa - Physiological reviews, 2005 - Am Physiological Soc Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate
the release of growth hormone (GH) from the pituitary. They act through the
GHS-R, a G protein-coupled receptor whose ligand has only been discovered ... Cited by 325 - Related articles - All 6 versions
M Korbonits, AP Goldstone, M Gueorguiev, … - Frontiers in neuroendocrinology, 2004 - Elsevier Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing
activities. It is mainly secreted from the stomach mucosa but it is also
expressed widely in different tissues and therefore may have both endocrine ... Cited by 224 - Related articles - All 4 versions
- ►endojournals.org HY Chen, ME Trumbauer, AS Chen, DT … - Endocrinology, 2004 - Endocrine Soc Ghrelin, a stomach-derived orexigenic hormone, has stimulated great interest as
a potential target for obesity control. Pharmacological evidence indicates that
ghrelin's effects on food intake are mediated by neuropeptide Y (NPY) and ... Cited by 223 - Related articles - BL Direct - All 4 versions
- ►endojournals.org K Toshinai, Y Date, N Murakami, M Shimada, … - Endocrinology, 2003 - Endocrine Soc The hypothalamus regulates energy intake by integrating the degree of starvation
or satiation with the status of the environment through a variety of neuronal
and blood-derived signals. Ghrelin, a peptide produced in the stomach and ... Cited by 190 - Related articles - BL Direct - All 3 versions
N Wierup, H Svensson, H Mulder, F Sundler - Regulatory peptides, 2002 - phoenixpeptide.com Objectives: Ghrelin, an endogenous ligand of the growth hormone secretagogue
receptor (GHS-R), was recently identified in the stomach. Ghrelin is produced in
a population of endocrine cells in the gastric mucosa, but expression in ... Cited by 178 - Related articles - View as HTML - All 9 versions
DE Cummings, MH Shannon - Archives of Surgery, 2003 - archsurg.highwire.org Obesity is a global epidemic that has proven daunting to prevent and treat. The
prevalences of obesity (body mass index [BMI] >30) and morbid obesity (BMI >40)
among American adults are about 30% and 5%, respectively. 1 Obesity is so ... Cited by 145 - Related articles - BL Direct - All 5 versions
- ►endojournals.org H Ariyasu, K Takaya, H Hosoda, H Iwakura, K … - Endocrinology, 2002 - Endocrine Soc THE CRUCIAL discovery of ghrelin has provided insight into the novel regulatory
system of GH release (1). Artificial compounds named GH secretagogues (GHSs)
release GH in vitro and in vivo through a specific receptor (2, 3, 4, 5, ... Cited by 132 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] N Murakami, T Hayashida, T Kuroiwa, K … - Journal of Endocrinology, 2002 - Soc Endocrinology Ghrelin, a 28-amino-acid peptide, has recently been isolated from the rat
stomach as an endogenous ligand for the GH secretagogue receptor. We have
reported pre- viously that central or peripheral administration of ghrelin ... Cited by 132 - Related articles - BL Direct - All 6 versions
- ►leptinresearch.org [PDF] A Sahu - Frontiers in neuroendocrinology, 2003 - Elsevier Leptin, the long-sought satiety factor of adipocytes origin, has emerged as one
of the major signals that relay the status of fat stores to the hypothalamus and
plays a significant role in energy homeostasis. Understanding the ... Cited by 128 - Related articles - All 7 versions