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Scholar Results 1 - 10 of 12 citing Bonifacio: International Workshop on Lessons From Animal Models for Human Type 1 Diabetes. (0.06 sec) 

A comprehensive guide to antibody and T-cell responses in type 1 diabetes


SM Lieberman, TP DiLorenzo - Tissue Antigens, 2003 - interscience.wiley.com
Abstract: Type 1 diabetes (T1D) is an organ-specific autoimmune disease in which
the insulin-producing β cells in the pancreatic islets are selectively
eliminated. T cells specific for β-cell antigens are the mediators of this ...
Cited by 60 - Related articles - BL Direct - All 5 versions

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends …


PA Silveira, E Johnson, HD Chapman, T Bui, … - European journal of immunology, 2002 - interscience.wiley.com
B lymphocytes partially contribute to autoimmune type 1 diabetes (T1D) as a
subset of APC with a preferential ability to trigger pathogenic CD4 T cells. We
hypothesized that this resulted fromthe unique ability of B lymphocytes to ...
Cited by 56 - Related articles - BL Direct - All 4 versions

Insulin Autoimmunity


GS EISENBARTH - Immunology of diabetes II: pathogenesis from mouse …, 2003 - interscience.wiley.com
Abstract: We can now predict the development of type 1A diabetes in humans and
prevent the disorder in animal models, but we cannot at present safely prevent
type 1A diabetes in humans, although a series of clinical trials are under ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Are Insights Gained from NOD Mice Sufficient to Guide Clinical Translation?


BO ROEP - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2007 - interscience.wiley.com
Abstract : Despite decades of research using various animal models for type 1
diabetes, we are still struggling to define the initiating autoantigens, the
precise mechanisms of β cell destruction, and suitable immune-based ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Coxsackievirus immunization delays onset of diabetes in non-obese diabetic mice


B Davydova, T Harkonen, S Kaialainen, T … - Journal of medical virology, 2003 - interscience.wiley.com
Enteroviruses may be involved in the pathogenesis of Type 1 diabetes through
different mechanisms including triggering of autoimmunity. The effect of
immunization with coxsackievirus B4-E2 on diabetes incidence was studied in ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Maternal immunity to insulin does not affect diabetes risk in progeny of non obese diabetic …


K Koczwara, AG Ziegler, E Bonifacio - Clinical and Experimental Immunology, 2004 - pubmedcentral.nih.gov
Blackwell Science, LtdOxford, UKCEIClinical and Experimental
Immunology0009-9104Blackwell Publishing Ltd, 20042004 1361 5659 Original Article
Maternal antibodies and diabetes risk K. Koczwara, A.-G. Ziegler & E. ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Identification of a major humoral epitope in Slc30A8 (ZnT8)


JM Wenzlau, O Moua, Y Liu, GS Eisenbarth, … - System, 1927 - interscience.wiley.com
The human zinc transporter Slc30A8 (ZnT8) is a major target of humoral
autoimmunity in human type 1A diabetes. However, despite extensive conservation,
the majority of human autoimmune sera fail to recognize the murine ...
Cited by 4 - Related articles - All 5 versions

Modulation of diabetes in NOD mice by GAD65-specific monoclonal antibodies is epitope …


TR Hall, M Bogdani, RC LeBoeuf, EA Kirk, M … - Immunology, 2008 - pubmedcentral.nih.gov
Type 1 diabetes is caused by the autoimmune destruction of pancreatic beta
cells. Here we show that administration of a human monoclonal antibody (b96·11)
specific to the 65-kDa isoform of glutamate decarboxylase (GAD65) to ...
Cited by 2 - Related articles - BL Direct - All 5 versions

Alkaline phosphatase to induce weight loss or to reduce weight gain


Z Kiss - US Patent 7,014,852, 2006 - Google Patents
US 7,014,852 B2 Page 2 OTHER PUBLICATIONS Kottel, RH and Hanford, WC,
"Differential release of membrane-bound alkaline phosphatase isoenzymes from
tumor cells by bromelain." Biochem. Biophys. Methods 2, 325-330 (1980). ...
Related articles - All 2 versions

Autoimmunity Triggers in the NOD Mouse


J Côrte-Real, N Duarte, L Tavares, C Penha- … - New York Academy Sciences Annals, 2009 - interscience.wiley.com
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