- ►physiology.org S Seino, T Shibasaki - Physiological reviews, 2005 - Am Physiological Soc Stimulus-secretion coupling is an essential process in secretory cells in which
regulated exocytosis occurs, including neuronal, neuroendocrine, endocrine, and
exocrine cells. While an increase in intracellular Ca 2+ concentration ([Ca ... Cited by 145 - Related articles - BL Direct - All 4 versions
DMF Cooper - Biochemical Journal, 2003 - pubmedcentral.nih.gov Adenylyl cyclases are a critically important family of multiply regulated
signalling molecules. Their susceptibility to many modes of regulation allows
them to integrate the activities of a variety of signalling pathways. ... Cited by 143 - Related articles - BL Direct - All 11 versions
GC Yaney, BE Corkey - Diabetologia, 2003 - Springer Increases in glucose or fatty acids affect metabolism via changes in long-chain
acyl-CoA formation and chronically elevated fatty acids increase total cellular
CoA. Understanding the response of pancreatic beta cells to increased ... Cited by 115 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org I Briaud, MK Lingohr, LM Dickson, CE Wrede … - Diabetes, 2003 - Am Diabetes Assoc Glucose can activate the mitogen-activated kinases, Erk-1/2, and the
ribosomal-S6 kinase, p70 S6K , in β-cells, contributing to an increase in
mitogenesis. However, the signaling mechanism by which glucose induces ... Cited by 76 - Related articles - BL Direct - All 4 versions
- ►physiology.org NM Doliba, W Qin, MZ Vatamaniuk, C Li, D … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Inhibition of ATP-sensitive K + (K ATP ) channels by an increase in the ATP/ADP
ratio and the resultant membrane depolarization are considered essential in the
process leading to insulin release (IR) from pancreatic -cells stimulated ... Cited by 37 - Related articles - BL Direct - All 6 versions
- ►shouxi.net D Liu, W Zhen, Z Yang, JD Carter, H Si, KA … - Diabetes, 2006 - Am Diabetes Assoc Although genistein, a soy isoflavone, has beneficial effects on various tissues,
it is unclear whether it plays a role in physiological insulin secretion. Here,
we present evidence that genistein increases rapid glucose-stimulated ... Cited by 34 - Related articles - BL Direct - All 6 versions
N Hatae, K Yamaoka, Y Sugimoto, M Negishi, … - Biochemical and Biophysical Research …, 2002 - Elsevier We previously demonstrated that the mouse EP3β receptor and its C-terminal
tail-truncated receptor (abbreviated T-335) expressed in Chinese hamster ovary
cells showed agonist-dependent and fully constitutive Gi activity in ... Cited by 22 - Related articles - BL Direct - All 8 versions
M Marzioni, G Alpini, S Saccomanno, S de … - Gastroenterology, 2006 - Elsevier Background & Aims There is poor knowledge on the factors that modulate the
growth of cholangiocytes, the epithelial cell target of cholangiopathies, which
are diseases leading to progressive loss of bile ducts and liver failure. ... Cited by 18 - Related articles - All 28 versions
P Zhang, C Liu, C Zhang, Y Zhang, P Shen, J … - FEBS letters, 2005 - Elsevier PGC-1α mRNA and protein are elevated in islets from multiple animal models of
diabetes. Overexpression of PGC-1α impairs glucose-stimulated insulin secretion
(GSIS). However, it is not well known which metabolic events lead to ... Cited by 17 - Related articles - All 6 versions
J Gromada - Endocrinology, 2006 - Endocrine Soc Free fatty acids (FFAs) provide an important energy source and also act as
signaling molecules. Accumulating evidence suggests that FFAs exert a variety of
physiological responses via an emerging family of G protein-coupled ... Cited by 16 - Related articles - BL Direct - All 4 versions
