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Scholar Results 1 - 10 of about 30 citing Schreyer: Mutation of the RIIβ subunit of protein kinase A prevents diet-induced insulin.... (0.12 sec) 

Pancreatic β-cell failure and diabetes in mice with a deletion mutation of the endoplasmic …

- diabetesjournals.org
WC Ladiges, SE Knoblaugh, JF Morton, MJ … - Diabetes, 2005 - Am Diabetes Assoc
The endoplasmic reticulum (ER) transmits apoptotic signals in the pancreas
during ER stress, implicating ER stress–mediated apoptosis in the development
of diabetes. P58 IPK (DNAJC3) is induced during ER stress and functions as ...
Cited by 62 - Related articles - All 6 versions

Reinventing the wheel of cyclic AMP: novel mechanisms of cAMP signaling.


KV Chin, WL Yang, R Ravatn, T Kita, E Reitman … - Annals of the New York Academy of Sciences, 2002 - ncbi.nlm.nih.gov
Mechanisms of cAMP signal transduction have been thoroughly investigated for
more than 40 years. From the binding of hormonal ligands to their receptors on
the outer surface of the plasma membrane to the cytoplasmic activation of ...
Cited by 56 - Related articles - BL Direct - All 2 versions

Minireview: PRKAR1A: normal and abnormal functions

- endojournals.org
I Bossis, CA Stratakis - Endocrinology, 2004 - Endocrine Soc
The type 1 regulatory subunit (RI ) of cAMP-dependent protein kinase (PKA)
(coded by the PRKAR1A gene) is the main component of type I PKA, which regulates
most of the serine-threonine kinase activity catalyzed by the PKA ...
Cited by 52 - Related articles - BL Direct - All 4 versions

Diabetes-related changes in cAMP-dependent protein kinase activity and decrease in …

- physiology.org
T Matsumoto, K Wakabayashi, T Kobayashi, … - American Journal of Physiology- Heart and Circulatory …, 2004 - Am Physiological Soc
Using superior mesenteric artery rings isolated from age-matched controls and
streptozotocin (STZ)-induced diabetic rats, we recently demonstrated that
EDHF-type relaxation is impaired in STZ-induced diabetic rats, possibly due ...
Cited by 31 - Related articles - BL Direct - All 7 versions

Cilostazol improves endothelium-derived hyperpolarizing factor-type relaxation in mesenteric …

- physiology.org
T Matsumoto, T Kobayashi, K Wakabayashi, … - American Journal of Physiology- Heart and Circulatory …, 2005 - Am Physiological Soc
We previously reported that in mesenteric arteries from streptozotocin
(STZ)-induced diabetic rats that 1) endothelium-derived hyperpolarizing factor
(EDHF)-type relaxation is impaired, possibly due to a reduced action of ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Dissecting interdomain communication within cAPK regulatory subunit type IIβ using …


KM Zawadzki, Y Hamuro, JS Kim, S Garrod, DD … - Protein Science: A Publication of the Protein Society, 2003 - pubmedcentral.nih.gov
The cAMP-binding domains contain extensive sequence and structural homology
across the isoforms. Each domain consists of two subdomains, one helical and the
other an eight-stranded β barrel, and is highly conserved as a signaling ...
Cited by 18 - Related articles - BL Direct - All 6 versions

Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation

- physiology.org
M Lu, JYJ Shyy - American Journal of Physiology- Cell Physiology, 2006 - Am Physiological Soc
Sterol regulatory element-binding protein (SREBP)-1a and -1c are key
transcription factors that regulate lipid biosynthesis in cells. We identified
that Ser338 located at the NH 2 terminus of SREBP-1a is a PKA ...
Cited by 15 - Related articles - BL Direct - All 3 versions

A therapeutic target for microvascular complications in diabetes: endothelium-derived …

- hoshi.ac.jp [PDF] 
T Matsumoto, T Kobayashi, K Kamata - Current Cardiology Reviews, 2006 - ingentaconnect.com
Abstract: Vascular alterations in diabetes cause or contribute to the etiology
of microvascular complications such as nephropathy, neuropathy, and retinopathy.
The endothelium controls the vascular smooth muscle tone through the ...
Cited by 12 - Related articles - All 2 versions

Deletion of the RII {beta}-Subunit of Protein Kinase A Decreases Body Weight and …

- endojournals.org
KJ Newhall, DE Cummings, MA Nolan, GS … - Molecular Endocrinology, 2005 - Endocrine Soc
Disruption of the RIIß regulatory subunit of protein kinase A (PKA) results in
mice with a lean phenotype, nocturnal hyperactivity, and increased resting
metabolic rate. In this report, we have examined whether deletion of RIIß ...
Cited by 12 - Related articles - All 6 versions

The Role of Uncoupling Protein 1 in the Metabolism and Adiposity of RII {beta}-Protein …

- endojournals.org
MA Nolan, MA Sikorski, GS McKnight - Molecular Endocrinology, 2004 - Endocrine Soc
Mice lacking the RIIß regulatory subunit of protein kinase A exhibit a 50%
reduction in white adipose tissue stores compared with wild-type littermates and
are resistant to diet-induced obesity. RIIß –/– mice also have an ...
Cited by 8 - Related articles - BL Direct - All 4 versions


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