- ►jimmunol.org IE Dumitriu, P Baruah, B Valentinis, RE Voll … - The Journal of Immunology, 2005 - Am Assoc Immnol High mobility group box 1 (HMGB1) is an abundant and conserved nuclear protein
that is released by necrotic cells and acts in the extracellular environment as
a primary proinflammatory signal. In this study we show that human ... Cited by 152 - Related articles - All 3 versions
BI Hudson, AM Schmidt - Pharmaceutical research, 2004 - Springer Received January 11, 2004; accepted March 10, 2004 At high levels as seen in
diabetes, glucose reacts with and forms adducts (advanced glycation end
products; AGEs) on macromolecules including proteins and DNA, eliciting ... Cited by 68 - Related articles - BL Direct - All 4 versions
K Pettersson-Fernholm, C Forsblom, BI … - Diabetes, 2003 - Am Diabetes Assoc The hyperglycemic milieu in diabetes results in the formation of advanced
glycation end products (AGEs) that predominantly act through specific receptors,
particularly the receptor for AGEs (RAGE). Two functional polymorphisms in ... Cited by 62 - Related articles - BL Direct - All 6 versions
BI Hudson, T Wendt, LG Bucciarelli, LL Rong … - Antioxidants & Redox Signaling, 2005 - liebertonline.com D IABETES MELLITUS is a chronic metabolic disorder char- acterized by an
inherited and/or acquired deficiency in the production or effect of insulin.
This deficiency results in an increase in blood glucose levels, which in ... Cited by 39 - Related articles - BL Direct - All 3 versions
K Walder, D Segal, J Jowett, J Blangero, GR … - Current pharmaceutical design, 2003 - ingentaconnect.com Abstract: New treatments are currently required for the common metabolic
diseases obesity and type 2 diabetes. The identification of physiological and
biochemical factors that underlie the metabolic disturbances observed in ... Cited by 23 - Related articles - BL Direct - All 4 versions
C Bopp, A Bierhaus, S Hofer, A Bouchon, PP … - Crit Care, 2008 - biomedcentral.com Abstract Sepsis still represents an important clinical and economic challenge
for intensive care units. Severe complications like multi- organ failure with
high mortality and the lack of specific diagnostic tools continue to hamper ... Cited by 14 - Related articles - View as HTML - All 10 versions
- ►bentham.org [PDF] B Lange-Sperandio, M Sperandio, P Nawroth, … - Current Pediatric Reviews, 2007 - ingentaconnect.com Abstract: The receptor for advanced glycation endproducts (RAGE) has been shown
to play an important role in aging, neurodegeneration, diabetes, and
inflammation. RAGE is a transmembrane receptor of the immunoglobuline ... Related articles - BL Direct - All 4 versions
A Bierhaus, PP Nawroth - Diabetologia, 2009 - Springer Abstract The pattern recognition receptor or receptor for AGE (RAGE) is
constitutionally expressed in a few cell types only. However in almost all cells
studied so far it is induced by reactions known to initiate inflammation. ... Cited by 1 - Related articles - All 2 versions
K Pettersson-Fernholm - ethesis.helsinki.fi To be presented with the permission of the Medical Faculty of the University of
Helsinki, for public examination in auditorium 2, Biomedicum, Haartmansgatan 8,
on December 21st, 2004, at 12 noon. ... Supervisor Per-Henrik Groop, DMSc ... Related articles - View as HTML - All 4 versions
