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Scholar Results 1 - 10 of about 29 citing Yang: Intrinsic defects in the T-cell lineage results in natural killer T-cell deficiency.... (0.11 sec) 

Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed …


L Bilenki, J Yang, Y Fan, S Wang, X Yang - European journal of immunology, 2004 - interscience.wiley.com
Although NKT cells have been found to be capable of modulating immune responses
in several model systems, the role of NKT cells in allergy remains unclear.
Using CD1 gene knockout (KO) mice, which lack NKT cells, we examined the ...
Cited by 34 - Related articles - BL Direct - All 3 versions

CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus …


R Fleuridor, B Wilson, R Hou, A Landay, H … - Immunology, 2003 - pubmedcentral.nih.gov
Invariant human natural killer T cells (NKT) express a restricted T-cell
receptor (TCR) Vα24Vβ11 repertoire. These cells share both phenotypic and
functional similarities between NK and T cells. Given the emerging role of ...
Cited by 32 - Related articles - BL Direct - All 5 versions

Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of …

- jimmunol.org
C Forestier, A Molano, JS Im, Y Dutronc, B … - The Journal of Immunology, 2005 - Am Assoc Immnol
CD1d-restricted NKT cells expressing invariant TCR -chain rearrangements (iNKT
cells) have been reported to be deficient in humans with a variety of autoimmune
syndromes and in certain strains of autoimmune mice. In addition, injection ...
Cited by 31 - Related articles - BL Direct - All 3 versions

Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications …


SP Berzins, K Kyparissoudis, DG Pellicci, KJ … - Immunology and cell biology, 2004 - interscience.wiley.com
Summary In the diabetes-prone NOD mouse, there is a proven association between a
systemic deficiency of NKT cells and the onset of type 1 diabetes. Numerous
reports of similar defects within the NKT cell compartment of human type 1 ...
Cited by 30 - Related articles - BL Direct - All 5 versions

NK T cell activation promotes Chlamydia trachomatis infection in vivo

- jimmunol.org
L Bilenki, S Wang, J Yang, Y Fan, AG Joyee, … - The Journal of Immunology, 2005 - Am Assoc Immnol
We used two approaches to examine the role of NK T cells (NKT) in an
intracellular bacterial (Chlamydia trachomatis mouse pneumonitis (C. muridarum))
infection. One is to use CD1 gene knockout (KO) mice, which lack NKT, and ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice


Y Yang, P Santamaria - Diabetologia, 2003 - Springer
Type 1 diabetes results from a genetically and immu- nologically complex
autoimmune process that is spe- cifically directed against the pancreatic beta
cells. Non-obese diabetic mice spontaneously develop a form of autoimmune ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Distinct NKT cell subsets are induced by different Chlamydia species leading to differential …

- jimmunol.org
AG Joyee, H Qiu, S Wang, Y Fan, L Bilenki, X … - The Journal of Immunology, 2007 - Am Assoc Immnol
We investigated the role of NKT cells in immunity to Chlamydia pneumoniae and
Chlamydia muridarum infections using a combination of knockout mice and specific
cellular activation approaches. The NKT-deficient mice showed exacerbated ...
Cited by 20 - Related articles - BL Direct - All 6 versions

The role of intrahepatic CD8+ T cell trapping and NK1. 1+ cells in liver-mediated immune …


O Shibolet, R Alper, L Zolotarov, S Trop, B … - Clinical Immunology, 2004 - Elsevier
The liver was previously suggested as a site of lymphocyte clearance.
Liver-associated lymphocytes that express NK1.1 marker (NKT LAL) play a role in
immune modulation. Aim: To determine the role of the liver and of NKT LAL ...
Cited by 14 - Related articles - All 3 versions

Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice …


YC Kudva, G Rajagopalan, R Raju, RS … - Human Immunology, 2002 - Elsevier
To evaluate the contributions of DR3 and DQ8 to the etiopathogenesis of type 1
diabetes in a diabetes-predisposing milieu, we developed human leukocyte antigen
(HLA) transgenic mice on the nonobese diabetic (NOD) background in the ...
Cited by 14 - Related articles - All 4 versions

New autoimmune genes and the pathogenesis of type 1 diabetes


L Hornum, H Markholst - Current Diabetes Reports, 2004 - Springer
Introduction Type 1 diabetes (T1D) is an autoimmune disease where the
insulin-producing β cells of the islets of Langerhans are destroyed by the
immune system, leading to a lifelong demand for exogenous insulin. ...
Cited by 13 - Related articles - BL Direct - All 2 versions


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