- ►rupress.org AE Juedes, E Rodrigo, L Togher, LH Glimcher … - Journal of Experimental Medicine, 2004 - jem.rupress.org The T-box transcription factor T-bet is known to control lineage commitment and
interferon- production by T helper 1 (Th1) CD4 lymphocytes. We report here that
T-bet is essential for development of CD8 lymphocyte-dependent autoimmune ... Cited by 50 - Related articles - BL Direct - All 6 versions
T Staeva-Vieira, M Peakman, M Von Herrath - Clinical and Experimental Immunology, 2007 - pubmedcentral.nih.gov Type 1 diabetes (T1D) is often considered the prototype organ-specific
autoimmune disease in clinical immunology circles. The key disease features −
precise destruction of a single endocrine cell type occurring on a distinct ... Cited by 46 - Related articles - BL Direct - All 5 versions
- ►nih.gov U Christen, KH Edelmann, DB McGavern, T … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig We document here that infection of prediabetic mice with a virus expressing an
H-2K b –restricted mimic ligand to a self epitope present on β cells
accelerates the development of autoimmune diabetes. Immunization with the ... Cited by 38 - Related articles - BL Direct - All 13 versions
M von Herrath, D Homann - Pediatric Diabetes, 2004 - cms1.daegu.ac.kr Abstract: How many new b-cells need to be generated in order to withstand the
attack of an 'average-strength' destructive autoimmune response? An answer to
this question is central for the design of intervention approaches aimed at ... Cited by 11 - Related articles - View as HTML - BL Direct - All 4 versions
D Yin, J Tao, DD Lee, J Shen, M Hara, J … - Diabetes, 2006 - Am Diabetes Assoc Limitations in islet β-cell transplantation as a therapeutic option for type 1
diabetes have prompted renewed interest in islet regeneration as a source of new
islets. In this study we tested whether severely diabetic adult C57BL/6 ... Cited by 9 - Related articles - BL Direct - All 4 versions
V Marrella, PL Poliani, C Sobacchi, F Grassi, A … - Trends in immunology, 2008 - Elsevier Omenn syndrome (OS) is a peculiar immunodeficiency in which profound T and B
cell defects are associated with severe autoimmune manifestations. Although the
molecular and biochemical bases of OS have been elucidated, the mechanisms ... Cited by 6 - Related articles - All 3 versions
GS Eisenbarth, JM Jasinski - Endocrinology and metabolism clinics of North America, 2004 - Elsevier There are three major models of the time course of loss of islet β cells during
the development of type 1A (immune-mediated) diabetes mellitus [1]. The first
chronic model [2] is supported by progressive loss of β-cell mass (despite ... Cited by 6 - Related articles - BL Direct - All 4 versions
EH Liu, BJ Digon, B Hirshberg, R Chang, BJ … - Diabetologia, 2009 - Springer Page 1. ARTICLE Pancreatic beta cell function persists in many patients with
chronic type 1 diabetes, but is not dramatically improved ... Cited by 1 - Related articles - All 2 versions
D Yin, J Tao, DD Lee, J Shen, M Hara, J … - 糖尿病学杂志, 2006 - journal.shouxi.net Limitations in islet -cell transplantation as a therapeutic option for type 1
diabetes have prompted renewed interest in islet regeneration as a source of new
islets. In this study we tested whether severely diabetic adult C57BL/6 ... Related articles - Cached