MY Donath, J Størling, K Maedler, T Mandrup- … - Journal of Molecular …, 2003 - Springer Abstract Pancreatic islet β-cell death occurs in type 1 and 2 diabetes mellitus, leading to
absolute or relative insulin deficiency. β-cell death in type 1 diabetes is due predominantly to
autoimmunity. In type 2 diabetes ... Cited by 145 - Related articles - BL Direct - All 3 versions
D Kawamori, Y Kajimoto, H Kaneto, Y Umayahara, Y … - Diabetes, 2003 - Am Diabetes Assoc Oxidative stress is induced in pancreatic β-cells under diabetic conditions and causes β-cell
dysfunction. Antioxidant treatment of diabetic animals leads to recovery of insulin biosynthesis and
increases the expression of its ... Cited by 68 - Related articles - BL Direct - All 4 versions
S Abdelli, J Ansite, R Roduit, T Borsello, I Matsumoto, T … - Diabetes, 2004 - Am Diabetes Assoc Type 1 diabetes is an autoimmune disease resulting from a progressive decrease in β-cell mass and
function (1). The mediators of β-cell dysfunction and destruction include macrophages, T-cells and
their inflammatory products, such ... Cited by 50 - Related articles - BL Direct - All 8 versions
H Kaneto, N Katakami, D Kawamori, T … - Antioxidants & redox …, 2007 - liebertonline.com F AILURE OF PANCREATIC cells is the common characteris- tic of type 1 and type 2 diabetes. Type 1
diabetes melli- tus is induced by destruction of pancreatic cells, which is mediated by an
autoimmune mechanism and the ... Cited by 48 - Related articles - BL Direct - All 4 versions
- ►endojournals.org R Aikin, D Maysinger, L Rosenberg - Endocrinology, 2004 - Endocrine Soc Therapeutic strategies aimed at the inhibition of specific cell death mechanisms may increase islet
yield and improve cell viability and function after routine isolation. The aim of the current study
was to explore the possibility of ... Cited by 42 - Related articles - BL Direct - All 3 versions
ER Ropelle, JR Pauli, PO Prada, CT de … - The Journal of …, 2006 - Physiological Soc Lifestyle interventions including exercise programmes are cornerstones in the prevention of
obesity-related diabetes. In this study, we demonstrate that a single bout of exercise inhibits
high-fat diet-induced insulin ... Cited by 35 - Related articles - BL Direct - All 8 versions
- ►endojournals.org PO Prada, HG Zecchin, AL Gasparetti, MA Torsoni, M … - Endocrinology, 2005 - Endocrine Soc The mechanisms by which diet-induced obesity is associated with insulin resistance are not well
established, and no study has until now integrated, in a temporal manner, functional insulin action
data with insulin signaling in key ... Cited by 30 - Related articles - All 5 versions
EZ Fisman, A Tenenbaum, M Motro - Cardiovascular diabetology, 2003 - biomedcentral.com Address: 1Sackler Faculty of Medicine, Tel-Aviv University, 69978 Ramat-Aviv, Tel-Aviv, Israel,
2Cardiovascular Diabetology Research Foundation, 58484 Holon, Israel and 3Cardiac Rehabilitation
Institute, Sheba Medical Center, ... Cited by 32 - Related articles - View as HTML - All 15 versions
MA Nikulina, N Sandhu, Z Shamim, NA Andersen, A … - Cytokine, 2003 - Elsevier The stress-activated protein kinase c-Jun NH 2 -terminal kinase (JNK) is a central signal for
interleukin-1β (IL-1β)-induced apoptosis in insulin-producing β-cells. The cell-permeable peptide
inhibitor of JNK (JNKI1), that ... Cited by 20 - Related articles - All 3 versions