B Portha - Diabetes/Metabolism Reviews - interscience.wiley.com Now that the reduction in -mass has been clearly established in humans with type
2 diabetes mellitus (T2DM) [1-4], the debate focuses on the possible mechanisms
responsible for decreased -cell number and impaired -cell function and ... Cited by 50 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JM Lin, ME Fabregat, R Gomis, P Bergsten - Diabetes, 2002 - Am Diabetes Assoc Plasma insulin in healthy subjects shows regular oscillations, which are
important for the hypoglycemic action of the hormone. In individuals with type 2
diabetes, these regular variations are altered, which has been implicated ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►nih.gov C Ling, S Del Guerra, R Lupi, T Rönn, C … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Insulin secretion in pancreatic islets is dependent
upon mitochondrial function and production of ATP. The transcriptional
coactivator peroxisome proliferator activated receptor gamma coactivator-1 ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org C Granhall, AH Rosengren, E Renstrom, H … - Diabetes, 2006 - Am Diabetes Assoc The effects of genetic variation on molecular functions predisposing to type 2
diabetes are still largely unknown. Here, in a specifically designed diabetes
model, we couple separate gene loci to mechanisms of ß-cell pathology. ... Cited by 6 - Related articles - BL Direct - All 7 versions
- ►numesi.com [PDF] B Portha, G Lacraz, M Kergoat, F Homo- … - Molecular and Cellular Endocrinology, 2009 - Elsevier Increasing evidence indicates that decreased functional beta-cell mass is the
hallmark of type 2 diabetes (T2D) mellitus. Nowadays, the debate focuses on the
possible mechanisms responsible for abnormal islet microenvironment, ... Cited by 6 - Related articles - All 3 versions
- ►genetics.org C Granhall, HB Park, H Fakhrai-Rad, H … - Genetics, 2006 - Genetics Soc America Niddm1i, a 16-Mb locus within the major diabetes QTL in the diabetic GK rat,
causes impaired glucose tolerance in the congenic NIDDM1I strain. Niddm1i is
homologous to both human and mouse regions linked with type 2 diabetes ... Cited by 5 - Related articles - All 5 versions
- ►genetics.org [PDF] C Granhall, HB Park, H Fakhrai-Rad, H … - Genetics, 2006 - Genetics Soc America Page 1. 1 High-resolution QTL Analysis Reveals Multiple Diabetes
Susceptibility Loci Mapped to Intervals less than 800-kb in the ... Cited by 3 - Related articles
C Granhall, HB Park, H Fakhrai-Rad, H … - Genetics, 2006 - ukpmc.ac.uk Niddm1i, a 16-Mb locus within the major diabetes QTL in the diabetic GK rat,
causes impaired glucose tolerance in the congenic NIDDM1I strain. Niddm1i is
homologous to both human and mouse regions linked with type 2 diabetes ... Related articles
LC Solberg Woods, N Ahmadiyeh, A Baum, K … - Mammalian Genome, 2009 - Springer Abstract While diabetic patients often present with comorbid depression, the
underlying mechanisms linking diabetes and depression are unknown. The Wistar
Kyoto (WKY) rat is a well-known animal model of depression and stress ... Related articles
