JL Evans, ID Goldfine, BA Maddux, GM Grodsky - Diabetes, 2003 - Am Diabetes Assoc In both type 1 and type 2 diabetes, diabetic complications in target organs arise from chronic
elevations of glucose. The pathogenic effect of high glucose, possibly in concert with fatty
acids, is mediated to a significant extent via increased production of reactive oxygen ... Cited by 371 - Related articles - BL Direct - All 10 versions
- ►caltech.edu [PDF] BS McEwen, JC Wingfield - Hormones and behavior, 2003 - Elsevier Living organisms have regular patterns and routines that involve obtaining food and carrying
out life history stages such as breeding, migrating, molting, and hibernating. The acquisition,
utilization, and storage of energy reserves (and other resources) are critical to lifetime ... Cited by 364 - Related articles - BL Direct - All 8 versions
HP Hammes, X Du, D Edelstein, T Taguchi, T … - Nature Medicine, 2003 - med.uio.no Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and nerve
damage. Diabetes-accelerated atherosclerosis leads to increased risk of myocardial
infarction, stroke and limb amputation. Large prospective clinical studies show a strong ... Cited by 333 - Related articles - BL Direct - All 9 versions
- ►cardiovascres.org G Basta, AM Schmidt, R De Caterina - Cardiovascular Research, 2004 - cardiovascres.org The formation of advanced glycation end products (AGEs) is an important biochemical abnormality
that accompanies diabetes mellitus and, likely, inflammation in general. Here we summarize
and discuss recent studies indicating that the effects of AGEs on vessel wall homeostasis ... Cited by 220 - Related articles - All 7 versions
- ►rupress.org T Chavakis, A Bierhaus, N Al-Fakhri, D … - Journal of Experimental …, 2003 - jem.rupress.org The pattern recognition receptor, RAGE (receptor for advanced glycation endproducts), propagates
cellular dysfunction in several inflammatory disorders and diabetes. Here we show that RAGE
functions as an endothelial adhesion receptor promoting leukocyte recruitment. In an ... Cited by 207 - Related articles - BL Direct - All 6 versions
A Bierhaus, PM Humpert, M Morcos, T Wendt, T … - Journal of Molecular …, 2005 - Springer Page 1. J Mol Med (2005) 83: 876–886 DOI 10.1007/s00109-005-0688-7 REVIEW
Angelika Bierhaus . Per M. Humpert . Michael Morcos . Thoralf Wendt . Triantafyllos
Chavakis . Bernd Arnold . David M. Stern . Peter P. Nawroth ... Cited by 189 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org A Goldin, JA Beckman, AM Schmidt, MA Creager - Circulation, 2006 - Am Heart Assoc Advanced glycation end products (AGEs) are proteins or lipids that become glycated after exposure
to sugars. AGEs are prevalent in the diabetic vasculature and contribute to the development
of atherosclerosis. The presence and accumulation of AGEs in many different cell types ... Cited by 193 - Related articles - All 7 versions
- ►nih.gov B Liliensiek, MA Weigand, A Bierhaus, W … - Journal of Clinical …, 2004 - Am Soc Clin Investig 1 Department of Molecular Immunology, Division of Tumor Immunology, German Cancer Research
Center, Heidelberg, Germany. 2 Department of Internal Medicine I and 3 Department of
Anesthesiology, University of Heidelberg, Heidelberg, Germany. 4 Department of Central ... Cited by 171 - Related articles - BL Direct - All 12 versions
A Bierhaus, J Wolf, M Andrassy, N … - Proceedings of the …, 2003 - National Acad Sciences Little is known about the mechanisms converting psychosocial stress into cellular
dysfunction. Various genes, up-regulated in atherosclerosis but also by psychosocial stress,
are controlled by the transcription factor nuclear factor κB (NF-κB). Therefore, NF-κB is a ... Cited by 168 - Related articles - BL Direct - All 12 versions
- ►jimmunol.org IE Dumitriu, P Baruah, B Valentinis, RE Voll, … - The Journal of …, 2005 - Am Assoc Immnol High mobility group box 1 (HMGB1) is an abundant and conserved nuclear protein that is released
by necrotic cells and acts in the extracellular environment as a primary proinflammatory
signal. In this study we show that human dendritic cells, which are specialized in Ag ... Cited by 152 - Related articles - All 3 versions
