- ►diabetesjournals.org A Ceriello - Diabetes care, 2003 - Am Diabetes Assoc Evidence implicates hyperglycemia-derived oxygen free radicals as mediators of diabetic
complications. However, intervention studies with classic antioxidants, such as vitamin E, failed
to demonstrate any beneficial effect. Recent studies demonstrate that a single ... Cited by 284 - Related articles - All 9 versions
- ►diabetesjournals.org L Quagliaro, L Piconi, R Assaloni, L Martinelli, E Motz, … - Diabetes, 2003 - Am Diabetes Assoc The effects of intermittent and constant high glucose in the formation of nitrotyrosine and 8-hydroxydeoxyguanosine
(markers of oxidative stress), as well as the possible linkage between oxidative stress and apoptosis
in endothelial cells, have been evaluated. Stable high glucose increased nitrotyrosine, 8- ... Cited by 193 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org C Goto, Y Higashi, M Kimura, K Noma, K Hara, K … - Circulation, 2003 - Am Heart Assoc Methods and Results— We evaluated the forearm blood flow responses to acetylcholine, an
endothelium-dependent vasodilator, and isosorbide dinitrate, an endothelium-independent
vasodilator, before and after different intensities of exercise (mild, 25% O 2 max; ... Cited by 130 - Related articles - BL Direct - All 5 versions
- ►nih.gov P Pacher, C Szabó - Antioxidants & redox signaling, 2005 - liebertonline.com Hyperglycemia-induced overproduction of superoxide by mitochondrial electron-transport chain
triggers several pathways of injury involved in the pathogenesis of diabetic complications [protein
kinase C (PKC), hexosamine and polyol pathway fluxes, advanced glycation end product ( ... Cited by 38 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org C Namkoong, MS Kim, PG Jang, SM Han, HS Park, EH … - Diabetes, 2005 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) acts as a cellular energy sensor, being activated during
states of low energy charge. Hypothalamic AMPK activity is altered by hormonal and metabolic
signals and mediates the feeding response. To determine the effect of diabetes on ... Cited by 36 - Related articles - All 7 versions
S Man Son, MK Whalin, DG Harrison, WR Taylor, KK … - Current Diabetes …, 2004 - Springer Introduction Macrovascular and microvascular diseases are currently the principal causes of
morbidity and mortality in patients with diabetes mellitus. Large, prospective, randomized clinical
studies show that long-term glycemic control is an important predictor of diabetic vascular ... Cited by 28 - Related articles - BL Direct - All 2 versions
C Szabó - Pharmacological research, 2005 - Elsevier Activation of poly(ADP-ribose) polymerase (PARP) plays a role in the pathogenesis of β-cell
necrosis that occurs in response to autoimmune disease associated with Type I diabetes. In
addition, PARP activation also plays a role in the pathogenesis of endothelial injury that ... Cited by 27 - Related articles - All 4 versions
L Kiss, C Szabó - Memórias do Instituto Oswaldo Cruz, 2005 - SciELO Brasil Recent work has demonstrated that hyperglycemia-induced overproduction of superoxide by
the mitochondrial electron-transport chain triggers several pathways of injury [(protein kinase
C (PKC), hexosamine and polyol pathway fluxes, advanced glycation end product ... Cited by 16 - Related articles - Cached - All 11 versions
K Endo, Y Miyashita, H Sasaki, M Ebisuno, M … - … of atherosclerosis and …, 2006 - sinoas.com Address for correspondence: Yoh Miyashita, Sakura Hospital, Toho University School of
Medicine, 564–1 Shimoshizu, Sakura City, Chiba 285–0841, Japan. E-mail:
mumon@sf6.so-net.ne.jp Received August 25, 2005 Accepted for publication December ... Cited by 11 - Related articles - BL Direct - All 4 versions
RH Hsieh, LM Lien, SH Lin, CW Chen, HJ Cheng, … - Ann NY Acad …, 2005 - cms1.daegu.ac.kr ABSTRACT: The possibility of 8-hydroxy-2′-deoxyguanosine (8-OHdG) serving as a sensitive
biomarker of oxidative DNA damage and oxidative stress was in- vestigated. Reactive oxygen
species (ROS) have been reported to be a cause of diabetes induced by chemicals such ... Cited by 11 - Related articles - View as HTML - BL Direct - All 8 versions
