- ►ucsf.edu [PDF] ME Wilson, D Scheel, MS German - Mechanisms of development, 2003 - Elsevier The specialized endocrine and exocrine cells of the pancreas originally derive
from a pool of apparently identical cells in the early gut endoderm. Serial
changes in their gene expression program, controlled by a hierarchy of ... Cited by 189 - Related articles - All 8 versions
- ►annals.org [PDF] GE Umpierrez, D Smiley, AE Kitabchi - Annals of internal medicine, 2006 - Am Coll Physicians Several investigators have reported that more than half of African- American
persons with new diagnoses of diabetic ketoacidosis have clinical, metabolic,
and immunologic features of type 2 diabetes during follow-up. These ... Cited by 57 - Related articles - BL Direct - All 6 versions
- ►rupress.org T Brun, I Franklin, L St-Onge, A Biason- … - Journal of Cell Biology, 2004 - jcb.rupress.org The mechanism by which the ß-cell transcription factor Pax4 influences cell
function/mass was studied in rat and human islets of Langerhans. Pax4
transcripts were detected in adult rat islets, and levels were induced by ... Cited by 56 - Related articles - All 11 versions
D Lang, SK Powell, RS Plummer, KP Young, … - Biochemical pharmacology, 2007 - Elsevier PAX proteins function as transcription factors and play an essential role in
organogenesis during embryonic development in regulating cell proliferation and
self-renewal, resistance to apoptosis, migration of embryonic precursor ... Cited by 42 - Related articles - All 5 versions
- ►oxfordjournals.org F Mauvais-Jarvis, SB Smith, CL May, SM Leal, … - Human Molecular Genetics, 2004 - Oxford Univ Press Ketosis-prone diabetes (KPD) is a rare form of type 2 diabetes, mostly observed
in subjects of west African origin (west Africans and African-Americans),
characterized by fulminant and phasic insulin dependence, but lacking ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►endojournals.org H Furuta, M Furuta, T Sanke, K Ekawa, T … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Mutations in transcription factors expressed in the pancreatic ß-cell are a
major cause of maturity-onset diabetes of the young (MODY). They have also been
found in patients diagnosed with type 1 and type 2 diabetes mellitus, which ... Cited by 29 - Related articles - BL Direct - All 4 versions
A Biason-Lauber, B Boehm, M Lang-Muritano, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 900–905 DOI 10.1007/s00125-005-1723-5 ARTICLE A.
Biason-Lauber . B. Boehm . M. Lang-Muritano . BR Gauthier . T. Brun . ... Cited by 29 - Related articles - All 4 versions
KA Johansson, A Grapin-Botton - Clinical genetics, 2002 - interscience.wiley.com The pancreas is a vital gland of exocrine and endocrine function. It is the
target of two main affections: diabetes and pancreatic cancer. We describe the
tissue interactions, signaling pathways and intracellular targets that are ... Cited by 24 - Related articles - BL Direct - All 4 versions
B Sosa-Pineda… - Mol Cells, 2004 - molcells.inforang.com The Pax-gene family encodes a group of transcription factors characterized by
the presence of a highly con- served DNA-binding motif, the paired domain. Pax
pro- teins are key regulators of vertebrate organogenesis since they play ... Cited by 24 - Related articles - View as HTML - All 7 versions
P Holm, B Rydlander, H Luthman, I Kockum - Diabetes, 2004 - Am Diabetes Assoc We have previously reported suggestive linkage to chromosome 5p13-q13 in type 1
diabetic families. ISL1, a transcription factor involved in pancreas
development, maps to this region. Sequencing of the ISL1 gene in patients ... Cited by 22 - Related articles - BL Direct - All 4 versions
