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Scholar Results 1 - 10 of about 495 citing Shintani: Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide.... (0.09 sec) 

Plasma ghrelin levels in lean and obese humans and the effect of glucose on …

- endojournals.org
T Shiiya, M Nakazato, M Mizuta, Y Date, MS … - Journal of Clinical …, 2002 - Endocrine Soc
Plasma ghrelin concentrations in patients with simple obesity and anorexia nervosa were lower
and higher, respectively, than those of healthy subjects with normal body weight. Among those
with type 2 diabetes mellitus, obese patients had lower and lean patients higher fasting ...
Cited by 643 - Related articles - BL Direct - All 5 versions

Stomach is a major source of circulating ghrelin, and feeding state determines …

- endojournals.org
H Ariyasu, K Takaya, T Tagami, Y Ogawa, K … - Journal of Clinical …, 2001 - Endocrine Soc
Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat stomach
and is involved in a novel system for regulating GH release. Although previous studies in rodents
suggest that ghrelin is also involved in energy homeostasis and that ghrelin secretion is ...
Cited by 561 - Related articles - BL Direct - All 4 versions

Biological, physiological, pathophysiological, and pharmacological aspects of …

- angrylapdog.com
AJ van der Lely, M Tschop, ML … - Endocrine …, 2004 - edrv.endojournals.org.p. …
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-releasing
activity. This activity is mediated by the activation of the so-called GH secretagogue receptor
type 1a. This receptor had been shown to be specific for a family of synthetic, peptidyl and ...
Cited by 428 - Related articles - BL Direct - All 9 versions

Minireview: ghrelin and the regulation of energy balance--a hypothalamic …

- endojournals.org
TL Horvath, S Diano, P Sotonyi, M Heiman, M Tschop - Endocrinology, 2001 - Endocrine Soc
The recently discovered hormone, ghrelin, has been recognized as an important regulator of
GH secretion and energy homeostasis. Orexigenic and adipogenic ghrelin is produced by the
stomach, intestine, placenta, pituitary, and possibly in the hypothalamus. The ...
Cited by 369 - Related articles - BL Direct - All 3 versions

Weight gain decreases elevated plasma ghrelin concentrations of patients with …


B Otto, U Cuntz, E Fruehauf, R Wawarta, C … - European Journal of …, 2001 - eje.org
OBJECTIVE: Ghrelin is a new gastric hormone that has been identified as an endogenous ligand
for the growth hormone (GH) secretagogue receptor subtype 1a (GHS-R1a). Ghrelin administration
however not only stimulates GH secretion but also induces adiposity in rodents by ...
Cited by 344 - Related articles - BL Direct - All 9 versions

Ghrelin: structure and function

- physiology.org
M Kojima, K Kangawa - Physiological reviews, 2005 - Am Physiological Soc
Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the release
of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein-coupled
receptor whose ligand has only been discovered recently. Using a reverse pharmacology ...
Cited by 330 - Related articles - All 6 versions

The need to feed homeostatic and hedonic control of eating

- cell.com
CB Saper, TC Chou, JK Elmquist - Neuron, 2002 - Elsevier
Feeding provides substrate for energy metabolism, which is vital to the survival of every living
animal and therefore is subject to intense regulation by brain homeostatic and hedonic
systems. Over the last decade, our understanding of the circuits and molecules involved ...
Cited by 317 - Related articles - All 17 versions

[PDF] Anatomy and regulation of the central melanocortin system


RD Cone - Nature neuroscience, 2005 - dept.wofford.edu
The central melanocortin system is perhaps the best-characterized neuronal pathway involved
in the regulation of energy homeostasis. This collection of circuits is unique in having the capability
of sensing signals from a staggering array of hormones, nutrients and afferent neural ...
Cited by 288 - Related articles - All 9 versions

Deletion of ghrelin impairs neither growth nor appetite

- nih.gov
Y Sun, S Ahmed, RG Smith - Molecular and cellular biology, 2003 - Am Soc Microbiol
Pharmacological studies show that ghrelin stimulates growth hormone release, appetite, and
fat deposition, but ghrelin's physiological role in energy homeostasis has not been
established. Ghrelin was also proposed to regulate leptin and insulin release and to be ...
Cited by 277 - Related articles - BL Direct - All 8 versions

Weight loss increases circulating levels of ghrelin in human obesity


TK Hansen, R Dall, H Hosoda, M Kojima, K … - Clinical …, 2002 - interscience.wiley.com
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Cited by 249 - Related articles - BL Direct - All 4 versions


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