C Ricordi - Diabetes, 2003 - medscape.com It has indeed been a distinct honor to be the recipient of the 2002 Outstanding Scientific Achievement
Award, and I was happy to accept it, on behalf of the entire islet transplant field, as there have
been many surgeons, physicians, and scientists who have worked as a team, moving this ... Cited by 100 - Related articles - All 8 versions
- ►asnjournals.org A Yamada, AD Salama, MH Sayegh - Journal of the American Society of …, 2002 - Am Soc Nephrol The CD28-B7 and CD154-CD40 pathways have been described as the critical costimulatory
pathways for T cell activation. Blockade of these pathways has been reported to regulate both
autoimmune and alloimmune responses in experimental models and in human disease. ... Cited by 85 - Related articles - BL Direct - All 4 versions
- ►nih.gov E Seung, JP Mordes, AA Rossini, DL … - Journal of Clinical …, 2003 - Am Soc Clin Investig Allogeneic hematopoietic chimerism leading to central tolerance has significant therapeutic
potential. Realization of that potential has been impeded by the need for myeloablative conditioning
of the host and development of graft-versus-host disease (GVHD). To surmount these ... Cited by 61 - Related articles - BL Direct - All 9 versions
- ►diabetesresearch.org [PDF] A Pileggi, C Ricordi, M Alessiani, L Inverardi - Clinica Chimica Acta, 2001 - Elsevier The fate of islet grafts is determined by many concurrent phenomena, some of which are common
to organ grafts (ie rejection), while others are unique to nonvascularized cell transplants, including
transplant cell mass and viability, as well as nonspecific inflammation at the site of ... Cited by 58 - Related articles - All 6 versions
- ►jimmunol.org DR Wesemann, Y Dong, GM O'Keefe, VT … - The Journal of …, 2002 - Am Assoc Immnol CD40 is a type I membrane-bound molecule belonging to the TNFR superfamily that is expressed
on various immune cells including macrophages and microglia. The aberrant expression of CD40
is involved in the initiation and maintenance of various human diseases including ... Cited by 42 - Related articles - BL Direct - All 3 versions
L Makhlouf, K Kishimoto, RN Smith, R Abdi, M … - Diabetes, 2002 - Am Diabetes Assoc Although it has often been assumed that transplanted allogeneic islets can be destroyed by recurrent
autoimmunity in recipients with type 1 diabetes, definitive evidence is lacking and the settings
in which this may occur have not been defined. To address these issues, we compared ... Cited by 40 - Related articles - BL Direct - All 5 versions
L Makhlouf, ST Grey, V Dong, E Csizmadia, MB … - Transplantation, 2004 - journals.lww.com Background. The authors' laboratory previously demonstrated that long-term tolerance to class
I-dis- parate renal allografts in miniature swine can be in- duced by a short course of cyclosporine
A (CsA), and that this stable tolerance is dependent on the presence of an intact thymus. ... Cited by 37 - Related articles - BL Direct - All 4 versions
T Kobayashi, Y Aomatsu, H Iwata, T Kin, H Kanehiro, … - Transplantation, 2003 - journals.lww.com Background. The recurrence of autoimmunity and allograft rejection act as major barriers to the
wide- spread use of islet transplantation as a cure for type 1 diabetes. The aim of this study was
to evaluate the feasibility of immunoisolation by use of an agarose microcapsule to ... Cited by 35 - Related articles - BL Direct - All 5 versions
RD Molano, A Pileggi, T Berney, R Poggioli, E Zahr, R … - Diabetes, 2003 - Am Diabetes Assoc Clinical islet transplantation is a successful procedure that can improve the quality of life in recipients
with diabetes. A drawback of the procedure is the need for chronic administration of immunosuppressive
drugs that, among other side effects, are potentially diabetogenic. Definition of ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org T Pearson, TG Markees, DV Serreze, MA … - The Journal of …, 2003 - Am Assoc Immnol Curing type 1 diabetes by islet transplantation requires overcoming both allorejection and recurrent
autoimmunity. This has been achieved with systemic immunosuppression, but tolerance induction
would be preferable. Most islet allotransplant tolerance induction protocols have been ... Cited by 30 - Related articles - BL Direct - All 7 versions
