- ►physiology.org MJ Dunne, KE Cosgrove, RM Shepherd, A … - Physiological reviews, 2004 - Am Physiological Soc The earliest description of hyperinsulinism appears to have been that provided
by Laidlaw in 1938 who used the term nesidioblastosis to describe the severe,
recurrent hypoglycemia associated with an inappropriate elevation of serum ... Cited by 108 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org JM Nerbonne, CG Nichols, TL Schwarz, D … - Circulation research, 2001 - Am Heart Assoc In the mammalian myocardium, potassium (K + ) channels control resting
potentials, action potential waveforms, automaticity, and refractory periods
and, in most cardiac cells, multiple types of K + channels that subserve ... Cited by 88 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Nakazaki, A Crane, M Hu, V Seghers, S … - Diabetes, 2002 - Am Diabetes Assoc Whereas the loss of ATP-sensitive K + channel (K ATP channel) activity in human
pancreatic β-cells causes severe hypoglycemia in certain forms of
hyperinsulinemic hypoglycemia, similar channel loss in sulfonylurea ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►endojournals.org I Giurgea, K Laborde, G Touati, C Bellanne- … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Congenital hyperinsulinism (CHI) is related to two main histological pancreas
anomalies: focal adenomatous hyperplasia and diffuse ß-cell hypersecretion.
Pharmacological tests to measure acute insulin responses (AIR) to ... Cited by 33 - Related articles - BL Direct - All 4 versions
AL Gloyn, J Siddiqui, S Ellard - Human mutation, 2006 - interscience.wiley.com The beta-cell ATP-sensitive potassium channel is a key component of
stimulus-secretion coupling in the pancreatic beta-cell. The channel couples
metabolism to membrane electrical events, bringing about insulin secretion. ... Cited by 32 - Related articles - BL Direct - All 3 versions
MA Sperling, RK Menon - The Pediatric Clinics of North America, 2004 - Elsevier A remarkable series of coordinated metabolic adaptations occurs at birth. At the
instant when the placental blood supply is curtailed, the fetus, hitherto
largely dependent on maternal blood for its glucose, must initiate ... Cited by 32 - Related articles - BL Direct - All 4 versions
K Hussain - Seminars in Fetal and Neonatal Medicine, 2005 - Elsevier Congenital hyperinsulinism is a cause of persistent hypoglycaemia in the
neonatal period. It is a heterogeneous disease with respect to clinical
presentation, molecular biology, genetic aetiology and response to medical ... Cited by 28 - Related articles - All 10 versions
T Meissner, E Mayatepek - European journal of pediatrics, 2002 - Springer Abstract Congenital hyperinsulinism is one of the most common causes of
recurrent hypoglycaemia in early infancy. It is characterised by dysregulation
of insulin secretion. Over the last few years, substantial progress has ... Cited by 27 - Related articles - BL Direct - All 3 versions
- ►endojournals.org S Tornovsky, A Crane, KE Cosgrove, K Hussain … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Hyperinsulinism of infancy is a genetically heterogeneous disease characterized
by dysregulation of insulin secretion resulting in severe hypoglycemia. To date,
mutations in five different genes, the sulfonylurea receptor (SUR1, ABCC8), ... Cited by 26 - Related articles - All 4 versions
- ►endojournals.org KE Cosgrove, MH Antoine, AT Lee, PD Barnes, … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc A novel ATP-sensitive potassium channel (K ATP ) channel agonist, BPDZ 154
(6,7-dichloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide), was
synthesized, and its effects on insulin-secreting cells were evaluated ... Cited by 26 - Related articles - BL Direct - All 5 versions
