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Scholar Results 1 - 10 of about 71 citing Cases: Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. (0.11 sec) 

The metabolic syndrome

- drclaudiaanrig.com [PDF] 
RH Eckel, SM Grundy, PZ Zimmet - The Lancet, 2005 - Elsevier
The metabolic syndrome is a common metabolic disorder that results from the increasing prevalence of
obesity. The disorder is defined in various ways, but in the near future a new definition(s) will be
applicable worldwide. The ...
Cited by 1569 - Related articles - All 41 versions

Update on adipocyte hormones


PJ Havel - Diabetes, 2004 - Am Diabetes Assoc
Hormones produced by adipose tissue play a critical role in the regulation of energy intake, energy
expenditure, and lipid and carbohydrate metabolism. This review will address the biology, actions,
and regulation of three adipocyte ...
Cited by 341 - Related articles - BL Direct - All 7 versions

Leptin signalling

- leptipro.org [PDF] 
G Sweeney - Cellular signalling, 2002 - Elsevier
The identification of leptin as the product of the obesity (ob) gene has been followed by extensive
research identifying a wide spectrum of physiological effects elicited by this adipose-derived
hormone. These effects are mediated ...
Cited by 177 - Related articles - All 10 versions

The early effect of the Roux-en-Y gastric bypass on hormones involved in body …


F Rubino, M Gagner, P Gentileschi, S Kini, S … - Annals of …, 2004 - pubmedcentral.nih.gov
The RYGB is an effective bariatric procedure for which the mechanism of action has not been
elucidated yet. Reports of hormonal changes after RYGB suggest a possible endocrine effect of the
operation; however, it is unknown ...
Cited by 145 - Related articles - BL Direct - All 6 versions

Analysis of paradoxical observations on the association between leptin and insulin …

- fasebj.org
RB Ceddia, HA Koistinen, JR Zierath, G Sweeney - The FASEB Journal, 2002 - FASEB
Obesity is commonly associated with the development of insulin resistance and diabetes in humans and
rodents. Insulin resistance and diabetes are observed in lipoatrophic individuals or rodent models
of lipoatrophy. Here we focus on ...
Cited by 140 - Related articles - BL Direct - All 4 versions

Overfeeding rapidly induces leptin and insulin resistance


J Wang, S Obici, K Morgan, N Barzilai, Z Feng, L … - Diabetes, 2001 - Am Diabetes Assoc
In common forms of obesity, hyperphagia, hyperinsulinemia, and hyperleptinemia coexist. Here, we
demonstrate rapid induction of insulin and leptin resistance by short-term overfeeding. After 3 and
7 days on the assigned diet ...
Cited by 132 - Related articles - BL Direct - All 14 versions

Leptin and hyperleptinemia-from friend to foe for cardiovascular function

- endocrinology-journals.org [PDF] 
J Ren - Journal of Endocrinology, 2004 - Soc Endocrinology
The obese gene product, leptin, plays a central role in food intake and energy metabolism. The
physiological roles of leptin in human bodily function have been broadened over the past decade
since leptin was first discovered ...
Cited by 128 - Related articles - BL Direct - All 10 versions

An adipocentric view of signaling and intracellular trafficking


S Mora, JE Pessin - Diabetes/Metabolism Reviews - interscience.wiley.com
Adipocytes have traditionally been considered to be the primary site for whole body energy storage
mainly in the form of triglycerides and fatty acids. This occurs through the ability of insulin to
markedly stimulate both glucose ...
Cited by 119 - Related articles - BL Direct - All 3 versions

Leptin effects on pancreatic β-cell gene expression and function


J Seufert - Diabetes, 2004 - Am Diabetes Assoc
The hormone leptin is secreted from white adipocytes, and serum levels of leptin correlate with
adipose tissue mass. Leptin was first described to act on the satiety center in the hypothalamus
through specific receptors (leptin ...
Cited by 97 - Related articles - BL Direct - All 5 versions

Peripheral metabolic actions of leptin


DM Muoio, G Lynis Dohm - Best Practice & Research Clinical Endocrinology & …, 2002 - Elsevier
The adipocyte-derived hormone, leptin, regulates food intake and systemic fuel metabolism; ob /ob
mice, which lack functional leptin, exhibit an obesity syndrome that is similar to morbid obesity in
humans. Leptin receptors are ...
Cited by 83 - Related articles - BL Direct - All 10 versions


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