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Scholar Results 1 - 10 of about 13 citing Flattem: α-and β-Cell Responses to Small Changes in Plasma Glucose in the Conscious Dog. (0.13 sec) 

Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus

- nih.gov
KI Rother, DM Harlan - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
Worldwide, more than 750 individuals with type 1 diabetes mellitus (T1DM) have received allogeneic
islet transplants since 1974, in an effort to cure their chronic condition. Though this is still a
small number (especially when ...
Cited by 103 - Related articles - BL Direct - All 11 versions

Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic …


V Ionut, K Hucking, IF Liberty, RN Bergman - Diabetologia, 2005 - Springer
Abstract Aims: Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone released from the gut in
response to nutrients. Besides its well-established direct effect on pan- creatic beta cells, GLP-1
may also act by activating sensors ...
Cited by 33 - Related articles - All 4 versions

Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, …

- physiology.org
LA Hornbuckle, DS Edgerton, JE Ayala, … - American Journal of …, 2001 - Am Physiological Soc
The regulation of glucose-6-phosphatase (G-6-Pase) catalytic subunit and glucose 6-phosphate (G-6-P)
transporter gene expression by insulin in conscious dogs in vivo and in tissue culture cells in situ
were compared. In ...
Cited by 18 - Related articles - BL Direct - All 3 versions

Maintenance of the postabsorptive plasma glucose concentration: insulin or insulin …

- physiology.org
B Raju, PE Cryer - American Journal of Physiology- …, 2005 - Am Physiological Soc
The prevalent view is that the postabsorptive plasma glucose concentration is maintained within the
physiological range by the interplay of the glucose-lowering action of insulin and the
glucose-raising action of glucagon. ...
Cited by 17 - Related articles - BL Direct - All 3 versions

Exercise induces hypoglycemia in rats with islet transplantation

- diabetesjournals.org
A Omer, VF Duvivier-Kali, W Aschenbach, V … - Diabetes, 2004 - Am Diabetes Assoc
Recently, islet transplantation in patients with type 1 diabetes has had greater success than in the
past, but the important question of whether the kinetics of islet secretion are able to accommodate
the metabolic demands of special ...
Cited by 14 - Related articles - BL Direct - All 4 versions

AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon …

- physiology.org
RJ McCrimmon, ML Evans, RJ Jacob, X … - American Journal of …, 2002 - Am Physiological Soc
Individuals with type 1 diabetes demonstrate a hypoglycemia-specific defect in glucagon secretion.
To determine whether intraislet hyperinsulinemia plays a role in the genesis of this defect,
glucagon-secretory responses to ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Effects of insulin deficiency or excess on hepatic gluconeogenic flux during …


DS Edgerton, S Cardin, C Pan, D Neal, B Farmer, M … - Diabetes, 2002 - Am Diabetes Assoc
The direct acute effects of insulin on the regulation of hepatic gluconeogenic flux to
glucose-6-phosphate (G6P) in vivo may be masked by the hormone's effects on net hepatic
glycogenolytic flux and the ...
Cited by 11 - Related articles - BL Direct - All 5 versions

[PDF] Islet auto-transplantation into an omental or splenic site results in a normal beta …


SM Gustavson, RV Rajotte, D Hunkeler, JRT … - American Journal of …, 2005 - assets0.pubget.com
Page 1. American Journal of Transplantation 2005; 5: 2368–2377 Blackwell Munksgaard Copyright C
Blackwell Munksgaard 2005 doi: 10.1111/j.1600-6143.2005.01041.x Islet Auto-Transplantation into
an Omental or Splenic Site Results in a Normal Beta Cell but Abnormal Alpha ...
Cited by 11 - Related articles - View as HTML - BL Direct - All 5 versions

Dipeptidyl peptidase IV inhibitors and the incretin system in type 2 diabetes …


AK Langley, TJ Suffoletta, HR Jennings - Pharmacotherapy, 2007 - PPI
As understanding of type 2 diabetes mellitus pathophysiology expands, treatments continue to evolve
and new pharmacologic targets emerge. Patients with type 2 diabetes exhibit deficiencies of the
incretin system; thus, methods for ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Pancreatic response to mild non–insulin-induced hypoglycemia does not involve …

- diabetesjournals.org
SM Sherck, M Shiota, J Saccomando, S Cardin, EJ … - Diabetes, 2001 - Am Diabetes Assoc
Mild non–insulin-induced hypoglycemia achieved by administration of a glycogen phosphorylase
inhibitor results in increased glucagon and decreased insulin secretion in conscious dogs. Our aim
was to determine whether the ...
Cited by 9 - Related articles - BL Direct - All 4 versions


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