- ►nih.gov K Takahashi, H Suwa, T Ishikawa, H Kotani - Journal of Clinical Investigation, 2002 - Am Soc Clin Investig Histamine is an aminergic neurotransmitter that is localized in the CNS and in
peripheral tissues. To date, four histamine receptors have been identified, and
the H3 receptor, which was recently cloned, is predominantly expressed in ... Cited by 72 - Related articles - BL Direct - All 7 versions
R Hanada, H Teranishi, JT Pearson, M … - Nature medicine, 2004 - members.medscape.com Neuromedin U (NMU) is a hypothalamic neuropeptide that regulates body weight and
composition. Here we show that mice lacking the gene encoding NMU (Nmu -/- mice)
develop obesity. Nmu -/- mice showed increased body weight and adiposity, ... Cited by 69 - Related articles - BL Direct - All 14 versions
K Tomizawa, N Iga, YF Lu, A Moriwaki, M … - Nature neuroscience, 2003 - nature.com Oxytocin is an essential hormone for mammalian labor and lactation. Here, we
show a new function of oxytocin in causing plastic changes in hippocampal
synapses during motherhood. In oxytocin-perfused hippocampal slices, ... Cited by 68 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org T Masaki, S Chiba, T Yasuda, T Tsubone, T … - Diabetes, 2003 - Am Diabetes Assoc To examine the peripheral and central roles of adiponectin in energy intake and
expenditure, we investigated the effects of adiponectin on food intake,
adiposity, sympathetic nerve activity (SNA), and mRNA expressions of ... Cited by 66 - Related articles - BL Direct - All 5 versions
T Masaki, S Chiba, T Yasuda, H Noguchi, T … - Diabetes, 2004 - Am Diabetes Assoc Histamine H 1 receptors (H 1 -Rs) are found in peripheral tissues and in regions
of the hypothalamus that are concerned with regulating body composition. In the
present study, we investigated the detailed mechanisms of histamine H 1 -Rs ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►aspetjournals.org TA Esbenshade, GB Fox, MD Cowart - Molecular interventions, 2006 - ASPET The histamine H 3 receptor is an attractive G protein–coupled receptor drug
target that regulates neurotransmission in the central nervous system and plays
a role in cognitive and homeostatic functions. Drug discovery efforts by ... Cited by 48 - Related articles - All 2 versions
CU Correll, AK Malhotra - Psychopharmacology, 2004 - Springer Abstract Rationale: Antipsychotic medications have been associated with
considerable weight gain. The degree of inter-individual variability and known
genetic contribu- tions to obesity suggest a combination of genetic and ... Cited by 40 - Related articles - BL Direct - All 4 versions
H Schröder - The Journal of nutritional biochemistry, 2007 - Elsevier The prevalence of obesity has grown to an alarming level of at least 300 million
people worldwide. Additionally, a diabetes epidemic is underway, with an
estimate of 217 million people with diabetes worldwide. There are many ... Cited by 39 - Related articles - All 14 versions
R Suzuki, K Tobe, M Aoyama, A Inoue, K … - Journal of Biological Chemistry, 2004 - ASBMB We previously reported that insulin receptor substrate-2 (IRS-2)-deficient mice
develop diabetes as a result of insulin resistance in the liver and failure of
-cell hyperplasia. In this study we introduced the IRS-2 gene specifically ... Cited by 39 - Related articles - BL Direct - All 4 versions
- ►endojournals.org AK Fulop, A Foldes, E Buzas, K Hegyi, IH … - Endocrinology, 2003 - Endocrine Soc Histamine has been referred to as an anorexic factor that decreases appetite and
fat accumulation and affects feeding behavior. Tuberomammillary histaminergic
neurons have been implicated in central mediation of peripheral metabolic ... Cited by 36 - Related articles - BL Direct - All 5 versions
