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Scholar Results 1 - 10 of about 106 citing Carlsson: Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective.... (0.12 sec) 

Tissue renin-angiotensin system: its expression, localization, regulation and …

- endocrinology-journals.org [PDF] 
PS Leung, PO Carlsson - Journal of Molecular Endocrinology, 2001 - Soc Endocrinology
ABSTRACT The classical concept of the renin–angiotensin system (RAS) is that of a blood-borne
cascade, whose final and bioactive product, angiotensin II, plays an important endocrine role
in the mainten- ance of blood pressure and electrolyte as well as fluid balance. In addition ...
Cited by 109 - Related articles - BL Direct - All 9 versions

Decreased vascular density in mouse pancreatic islets after transplantation

- diabetesjournals.org
G Mattsson, L Jansson, PO Carlsson - Diabetes, 2002 - Am Diabetes Assoc
An adequate revascularization is crucial for islet survival and function after transplantation. Previous
studies have suggested that islet revascularization is concluded within 14 days after
transplantation. We investigated if the vascular density of transplanted islets and ...
Cited by 83 - Related articles - BL Direct - All 7 versions

Elevated vascular endothelial growth factor production in islets improves islet graft …


N Zhang, A Richter, J Suriawinata, S Harbaran, J … - Diabetes, 2004 - Am Diabetes Assoc
Successful islet transplantation depends on the infusion of sufficiently large quantities of
islets, of which only ∼30% become stably engrafted. Rapid and adequate revascularization
of transplanted islets is important for islet survival and function. Delayed and insufficient ...
Cited by 80 - Related articles - BL Direct - All 6 versions

Graft vascular function after transplantation of pancreatic islets


L Jansson, PO Carlsson - Diabetologia, 2002 - Springer
Endogenous pancreatic islets have a dense glomeru- lar-like angioarchitecture, which ensures
an optimal delivery of oxygen and nutrients to the islet cells, pro- vides signals from other cells
in the body and disposes secreted hormones. Transplantation of isolated islets means ...
Cited by 80 - Related articles - BL Direct - All 5 versions

Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo


EG Meyron-Holtz, MC Ghosh, TA Rouault - Science, 2004 - sciencemag.org
A list of selected additional articles on the Science Web sites ... 54 article(s) on the ISI Web of
Science. cited by This article has been ... 2004 by the American Association for the Advancement
of Science; all rights reserved. The title ... American Association for the Advancement of ...
Cited by 76 - Related articles - All 6 versions

Evidence for a local angiotensin-generating system and dose-dependent inhibition …


T Lau, PO Carlsson, PS Leung - Diabetologia, 2004 - Springer
Aims/hypothesis. A local angiotensin-generating system has been found in the exocrine
pancreas. This study aimed, primarily, to investigate the existence of a local angiotensin-generating
system in the pancreatic islets and, secondly, to elucidate its role in regulating insulin ...
Cited by 71 - Related articles - BL Direct - All 9 versions

Metallothionein protects islets from hypoxia and extends islet graft survival by …


X Li, H Chen, PN Epstein - Journal of Biological Chemistry, 2004 - ASBMB
Islet transplantation is a promising therapy for Type 1 diabetes, but many attempts have failed
due to early graft hypoxia or immune rejection, which generate reactive oxygen species
(ROS). In the current study, we determined that transgenic overexpression of the ...
Cited by 66 - Related articles - BL Direct - All 5 versions

Apoptosis in hypoxic human pancreatic islets correlates with HIF-1a expression

- fasebj.org [PDF] 
W Moritz, F Meier, D Stroka, M Giuliani, P Kugelmeier, … - The FASEB Journal, 2002 - FASEB
The FASEB Journal express article 10.1096/fj.01-0403fje. Published online March 26, 2002.
... Apoptosis in hypoxic human pancreatic islets correlates ... W. Moritz,* F. Meier,* D.
Stroka, †,fl M. Giuliani,* P. Kugelmeier,* Ph. C. Nett,* R. Lehmann, § D. Candinas, † M. ...
Cited by 64 - Related articles - BL Direct - All 5 versions

Low revascularization of experimentally transplanted human pancreatic islets

- endojournals.org
PO Carlsson, F Palm, G Mattsson - Journal of Clinical Endocrinology & …, 2002 - Endocrine Soc
Pancreatic islets are avascular immediately after transplantation. Although the islets are rapidly
revascularized, it is uncertain whether the revascularization produces an adequate oxygenation
of the transplanted islet tissue. We measured pO 2 , blood flow and vascular density in ...
Cited by 61 - Related articles - BL Direct - All 4 versions

{alpha}-Cells of the endocrine pancreas: 35 years of research but the enigma …

- endojournals.org
J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc
Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is critical for blood
glucose homeostasis. It is the major counterpart to insulin and is released during hypoglycemia
to induce hepatic glucose output. The control of glucagon secretion is multifactorial and ...
Cited by 61 - Related articles - BL Direct - All 4 versions


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