- ►nih.gov MA Herman, BB Kahn - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig The prevalence of obesity and type 2 diabetes continues to increase at alarming
rates (1). Type 2 diabetes is a prototypic complex, polygenic disease with a
strong heritable component, which is also heavily influenced by ... Cited by 56 - Related articles - BL Direct - All 9 versions
B Thorens - Molecular membrane biology, 2001 - informahealthcare.com Summary Detection of variations in blood glucose concentrations by pancreatic
b-cells and a subsequent appropriate secretion of insulin are key events in the
control of glucose homeostasis. Because a decreased capability to sense ... Cited by 48 - Related articles - BL Direct - All 7 versions
- ►physiology.org PQ Yuan, H Yang - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Neuronal activation of brain vagal-regulatory nuclei and gastric/duodenal
enteric plexuses in response to insulin (2 U/kg, 2 h) hypoglycemia was studied
in rats. Insulin hypoglycemia significantly induced Fos expression in the ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►physiology.org X Wu, J Gao, J Yan, C Owyang, Y Li - Journal of neurophysiology, 2004 - Am Physiological Soc Circulating glucose levels significantly affect vagal neural activity, which is
important in the regulation of pancreatic functions. Little is known about the
mechanisms involved. This study investigates the neural pathways ... Cited by 18 - Related articles - BL Direct - All 4 versions
- ►physiology.org LA Hornbuckle, DS Edgerton, JE Ayala, CA … - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc The regulation of glucose-6-phosphatase (G-6-Pase) catalytic subunit and glucose
6-phosphate (G-6-P) transporter gene expression by insulin in conscious dogs in
vivo and in tissue culture cells in situ were compared. In ... Cited by 18 - Related articles - BL Direct - All 3 versions
DS Edgerton, S Cardin, C Pan, D Neal, B … - Diabetes, 2002 - Am Diabetes Assoc The direct acute effects of insulin on the regulation of hepatic gluconeogenic
flux to glucose-6-phosphate (G6P) in vivo may be masked by the hormone's effects
on net hepatic glycogenolytic flux and the resulting changes in glycolysis. ... Cited by 11 - Related articles - BL Direct - All 5 versions
- ►physiology.org S Cardin, K Walmsley, DW Neal, PE Williams, … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc We determined if blocking transmission in the fibers of the vagus nerves would
affect basal hepatic glucose metabolism in the 18-h-fasted conscious dog. A
pancreatic clamp (somatostatin, basal portal insulin, and glucagon) was ... Cited by 10 - Related articles - BL Direct - All 3 versions
H Schachinger, J Port, S Brody, L Linder, FH … - Clinical Science, 2004 - cs.portlandpress.com ∗ Department of Internal Medicine, Clinical Research Center and Division of
Psychosomatic Medicine, University Hospital, 4031 Basel, Switzerland,
†Biomedical Institute, University of Stuttgart, D70174 Stuttgart, ... Cited by 3 - Related articles - View as HTML - BL Direct - All 13 versions
- ►physiology.org CA DiCostanzo, MC Moore, M Lautz, M Scott, B … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc We examined the extent to which priming the liver with a pulse of Humulin or the
insulin analog hexyl-insulin monoconjugate 2 (HIM2) reduces postprandial
hyperglycemia. Somatostatin (0.5 µg·kg –1 ·min –1 ) was given with ... Cited by 3 - Related articles - BL Direct - All 4 versions
CA DiCostanzo, DP Dardevet, PE Williams, M … - Metabolism, 2007 - Elsevier We examined the role of vagus nerves in the transmission of the portal glucose
signal in conscious dogs. At time 0, somatostatin infusion was started along
with intraportal insulin and glucagon at 4-fold basal and basal rates, ... Cited by 1 - Related articles - All 7 versions
