- ►nih.gov D Vicent, J Ilany, T Kondo, K Naruse, SJ … - Journal of Clinical …, 2003 - Am Soc Clin Investig Insulin receptors (IRs) on vascular endothelial cells have been suggested to participate in
insulin-regulated glucose homeostasis. To directly address the role of insulin action in endothelial
function, we have generated a vascular endothelial cell IR knockout (VENIRKO) mouse ... Cited by 141 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org T Ogihara, T Asano, K Ando, Y Chiba, H Sakoda, M … - Hypertension, 2002 - Am Heart Assoc Angiotensin II (AII) is involved in the pathogenesis of both hypertension and insulin
resistance, though few studies have examined the relationship between the two. We therefore
investigated the effects of chronic AII infusion on blood pressure and insulin sensitivity in ... Cited by 141 - Related articles - BL Direct - All 6 versions
- ►endocrinology-journals.org [PDF] FP Dominici, S Hauck, DP Argentino, A … - Journal of …, 2002 - Soc Endocrinology In the present study we have used hypopituitary Ames dwarf mice, which lack GH, prolactin and
TSH, to investigate the consequences of the deficiency of these hormones on glucose homeostasis
and on the initial components of the insulin signal transduction pathway in the liver. Ames ... Cited by 67 - Related articles - BL Direct - All 7 versions
- ►ebmonline.org FP Dominici, D Turyn - Experimental Biology and Medicine, 2002 - SEBM Growth hormone (GH) counteracts insulin action on lipid and glucose metabolism. However,
the sequence of molecular events leading to these changes is poorly understood. Insulin action
is initiated by binding of the hormone to its cell surface receptor (IR). This event activates ... Cited by 63 - Related articles - BL Direct - All 4 versions
- ►diabetes-mellitus.org [DOC] T Ogihara, T Asano, H Katagiri, H Sakoda, M Anai, N … - Diabetologia, 2004 - Springer Aims/hypothesis. Oxidative stress is associated with diabetes, hypertension and
atherosclerosis. Insulin re- sistance is implicated in the development of these dis- orders. We
tested the hypothesis that oxidative stress induces insulin resistance in rats, and ... Cited by 62 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org T Ogihara, T Asano, K Ando, H Sakoda, M Anai, N … - Hypertension, 2002 - Am Heart Assoc A high-salt diet, which is known to contribute to the pathogenesis of hypertension, is also reportedly
associated with insulin resistance. We investigated the effects of a high-salt diet on insulin sensitivity
and insulin signaling in salt-sensitive (Dahl-S) and salt resistant (Dahl-R) strains of the ... Cited by 60 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org T Shimosawa, T Ogihara, H Matsui, T Asano, K Ando, T … - Hypertension, 2003 - Am Heart Assoc Hypertension, insulin resistance, and obesity are common age-related metabolic disorders that
are often associated with increased oxidative stress and the resultant vascular damage. Underlying
mechanisms have been suggested, and age-related overproduction of oxidative stress is ... Cited by 59 - Related articles - BL Direct - All 6 versions
JM Zabolotny, FG Haj, YB Kim, HJ Kim, GI Shulman … - Journal of Biological …, 2004 - ASBMB Previous studies implicate protein-tyrosine phosphatase 1B (PTP1B) and leukocyte
antigen-related phosphatase (LAR) as negative regulators of insulin signaling. The expression
and/or activity of PTP1B and LAR are increased in muscle of insulin-resistant rodents and ... Cited by 55 - Related articles - BL Direct - All 8 versions
- ►asnjournals.org S Shibata, M Nagase, T Fujita - Journal of the American Society of …, 2006 - Am Soc Nephrol Statins have been reported to confer renoprotection in several experimental models of renal
disease through pleiotropic actions. The roles of statins in glomerular podocytes have not been
explored. The objective of this study was to evaluate the effects of fluvastatin on podocyte ... Cited by 50 - Related articles - BL Direct - All 5 versions
- ►physiology.org H Sakoda, T Ogihara, M Anai, M Fujishiro, … - American Journal of …, 2002 - Am Physiological Soc 5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) reportedly activates AMP-activated
protein kinase (AMPK) and stimulates glucose uptake by skeletal muscle cells. In this study, we
investigated the role of AMPK in AICAR-induced glucose uptake by 3T3-L1 adipocytes ... Cited by 49 - Related articles - BL Direct - All 4 versions
