- ►endojournals.org GF Lewis, A Carpentier, K Adeli, A Giacca - Endocrine reviews, 2002 - Endocrine Soc The primary genetic, environmental, and metabolic factors responsible for causing insulin resistance
and pancreatic ß-cell failure and the precise sequence of events leading to the development
of type 2 diabetes are not yet fully understood. Abnormalities of triglyceride storage and ... Cited by 525 - Related articles - BL Direct - All 6 versions
- ►pnas.org MP Czubryt, J McAnally, GI Fishman, … - Proceedings of the …, 2003 - National Acad Sciences The myocyte enhancer factor-2 (MEF2) transcription factor regulates muscle development and
calcium-dependent gene expression. MEF2 activity is repressed by class II histone deacetylases
(HDACs), which dissociate from MEF2 when phosphorylated on two serine residues in ... Cited by 159 - Related articles - BL Direct - All 6 versions
G Milan, M Granzotto, A Scarda, A Calcagno, C … - Obesity, 2002 - nature.com Discussion: Adiponectin and resistin are down-regulated in VAT of obese rats. Adiponectin expression
is restored to normal levels after body-weight reduction, supporting its link with obesity-related
insulin resistance. On the contrary, the further decrease of resistin mRNA after weight loss ... Cited by 146 - Related articles - BL Direct - All 4 versions
- ►endojournals.org C Pagano, C Pilon, M Olivieri, P Mason, R … - Journal of Clinical …, 2006 - Endocrine Soc Results: Plasma visfatin and its mRNA in SAT were significantly lower in obese subjects, compared
with normal-weight controls. Both circulating visfatin and SAT visfatin mRNA were negatively
correlated with body mass index, whereas no correlation was found with homeostasis ... Cited by 116 - Related articles - BL Direct - All 6 versions
- ►ajcn.org D Cameron-Smith, LM Burke, DJ Angus, RJ … - American Journal of …, 2003 - Am Soc Nutrition 1 From the School of Health Sciences, Deakin University, Burwood, Australia (DC-S, RJT, and
MH); Sports Science and Sports Medicine, Australian Institute of Sport, Belconnen, Australia
(LMB, DJA, and GRC); the Department of Kinesiology, University of Waterloo, Waterloo, ... Cited by 96 - Related articles - BL Direct - All 4 versions
- ►sc.edu [PDF] DPY Koonen, JFC Glatz, A Bonen, JJFP Luiken - BBA-Molecular and Cell …, 2005 - Elsevier Cellular long-chain fatty acid (LCFA) uptake constitutes a process that is not yet fully
understood. LCFA uptake likely involves both passive diffusion and protein-mediated
transport. Several lines of evidence support the involvement of a number of plasma ... Cited by 83 - Related articles - All 4 versions
D Nolan, M John, S Mallal - Antiviral therapy(London), 2001 - cat.inist.fr Clinical research has indicated that the use of nucleoside reverse transcriptase
inhibitor(NRTI) and HIV protease inhibitor(PI) therapy is associated with a risk of long-term toxicity
syndromes, and that the aetiopathogenesis of these adverse effects is independent of the ... Cited by 82 - Related articles - BL Direct - All 4 versions
BD Hegarty, GJ Cooney, EW Kraegen, SM Furler - Diabetes, 2002 - Am Diabetes Assoc In humans and animal models, increased lipid content of skeletal muscle is strongly associated
with insulin resistance. However, it is unclear whether this accumulation is due to increased uptake
or reduced utilization of fatty acids (FAs). We used 3 HR-bromopalmitate tracer to assess ... Cited by 77 - Related articles - BL Direct - All 5 versions
S Franckhauser, S Muñoz, A Pujol, A Casellas, E Riu, P … - Diabetes, 2002 - Am Diabetes Assoc Adipose tissue glyceroneogenesis generates glycerol 3-phosphate, which could be used for
fatty acid esterification during starvation. To determine whether increased glyceroneogenesis
leads to increased fat mass and to explore the role of obesity in the development of ... Cited by 74 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org DL Sprecher, C Massien, G Pearce, AN Billin, … - … , and Vascular Biology, 2007 - Am Heart Assoc From the Department of Discovery Medicine (DLS, CM, GP, TGJ), Cardiovascular and Urogenital
Center of Excellence in Drug Discovery, GlaxoSmithKline, King of Prussia, Pa; the Department
of High-throughput Biology (ANB), GlaxoSmithKline, Research Triangle Park, NC; the ... Cited by 71 - Related articles - All 6 versions
