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Scholar Results 1 - 10 of about 298 citing Vilsbøll: Reduced postprandial concentrations of intact biologically active glucagon-like.... (0.23 sec) 

Pathogenesis of type 2 diabetes mellitus

- fafp.org [PDF] 
RA DeFronzo - Medical Clinics of North America, 2004 - Elsevier
A discussion of the pathogenesis of type 2 diabetes mellitus must start with a
review of mechanisms involved in the maintenance of normal glucose homeostasis
in the basal or postabsorptive state (10–12 h overnight fast) and ...
Cited by 692 - Related articles - BL Direct - All 5 versions

Enhancing incretin action for the treatment of type 2 diabetes

- diabetesjournals.org
DJ Drucker - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic
peptide (GIP) exert important effects on β-cells to stimulate glucose-dependent
insulin secretion. Both peptides also regulate β-cell proliferation and ...
Cited by 283 - Related articles - All 13 versions

Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic …

- endojournals.org
L Farilla, H Hui, C Bertolotto, E Kang, A Bulotta … - Endocrinology, 2002 - Endocrine Soc
A constant remodeling of islet cell mass mediated by proliferative and apoptotic
stimuli ensures a dynamic response to a changing demand for insulin. In this
study, we investigated the effect of glucagon-like peptide-1 (GLP-1) in ...
Cited by 193 - Related articles - BL Direct - All 6 versions

Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces …


CB Juhl, M Hollingdal, J Sturis, G Jakobsen, H … - Diabetes, 2002 - Am Diabetes Assoc
Glucagon-like peptide 1 (GLP-1) is a potent glucose-lowering agent of potential
interest for the treatment of type 2 diabetes. To evaluate actions of NN2211, a
long-acting GLP-1 derivative, we examined 11 patients with type 2 diabetes, ...
Cited by 174 - Related articles - BL Direct - All 6 versions

Biology of incretins: GLP-1 and GIP

- rh.dk [PDF] 
LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier
This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ...
Cited by 173 - Related articles - All 25 versions

Improved glycemic control with no weight increase in patients with type 2 diabetes after …

- diabetesjournals.org
S Madsbad, O Schmitz, J Ranstam, G … - Diabetes Care, 2004 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—A double-blind, randomized, parallel-group,
placebo-controlled trial with an open-label comparator arm was conducted among
193 outpatients with type 2 diabetes. The mean age was 56.6 years and the ...
Cited by 170 - Related articles - BL Direct - All 6 versions

One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide ( …

- diabetesjournals.org
KB Degn, CB Juhl, J Sturis, G Jakobsen, B … - Diabetes, 2004 - Am Diabetes Assoc
Glucagon-like peptide 1 (GLP-1) is potentially a very attractive agent for
treating type 2 diabetes. We explored the effect of short-term (1 week)
treatment with a GLP-1 derivative, liraglutide (NN2211), on 24-h dynamics ...
Cited by 168 - Related articles - BL Direct - All 8 versions

Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions …


AM Lambeir, C Durinx, S Scharpé, I De … - Critical reviews in clinical laboratory sciences, 2003 - informahealthcare.com
Laboratory of Medical Biochemistry, University of Antwerp, Universiteitsplein 1,
Wilrijk, Belgium ... Referee: Dr. Albert Adam, Faculté de Pharmace,
Université de Montréal, 2900 Blvd. Edouard—Montpetit, CP succursale ...
Cited by 166 - Related articles - BL Direct - All 9 versions

Therapeutic strategies based on glucagon-like peptide 1

- diabetesjournals.org
CF Deacon - Diabetes, 2004 - Am Diabetes Assoc
Glucagon-like peptide (GLP)-1 is an incretin hormone with potent
glucose-dependent insulinotropic and glucagonostatic actions, trophic effects on
the pancreatic β-cells, and inhibitory effects on gastrointestinal ...
Cited by 154 - Related articles - BL Direct - All 5 versions

Incretins, insulin secretion and type 2 diabetes mellitus


T Vilsbøll, JJ Holst - Diabetologia, 2004 - Springer
When glucose is taken orally, insulin secretion is stim- ulated much more than
it is when glucose is infused intravenously so as to result in similar glucose
con- centrations. This effect, which is called the incretin ef- fect and is ...
Cited by 145 - Related articles - BL Direct - All 7 versions


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